HitPredict

Interactor 1: E2AK3 (Q9NZJ5)
Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK)
Gene: EIF2AK3

Interactor 2: PCDAC (Q9UN75)
Protocadherin alpha-12 (PCDH-alpha-12)
Gene: PCDHA12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1116 Hs			1 941
+	Hs
		1349215 E2AK3_HUMAN (1-1116): 0: 1253: 98.49		PCDA4_HUMAN (1-941): 0: 1042: 81.10
+	Hs
		1349223 E2AK3_HUMAN (1-1116): 0: 1253: 98.49		PCDG4_HUMAN (1-892): 0: 907: 37.24
+	Hs
		1349214 E2AK3_HUMAN (1-1116): 0: 1253: 98.49		PCDGG_HUMAN (2-447): 7.68e-97: 327: 26.96
+	Hs
		1349221 E2AK3_HUMAN (1-1116): 0: 1253: 98.49		PCDBB_HUMAN (461-902): 1.73e-37: 153: 14.46
+	Hs
		851741 NEK4_HUMAN (918-1072): 1.43e-15: 84: 30.25		PCDAC_HUMAN (1-941): 0: 1034: 100.00
+	Hs
		851758 NEK4_HUMAN (918-1072): 1.43e-15: 84: 30.25		PCDGM_HUMAN (6-889): 0: 1001: 38.32
+	Hs
		375158 RAF1_HUMAN (672-1083): 9.3e-80: 276: 20.58		PCDC2_HUMAN (452-913): 3.55e-46: 181: 15.87
+	Hs
		1255620 NEK7_HUMAN (910-1075): 4.51e-21: 97.1: 36.26		PCDGD_HUMAN (2-447): 1.53e-100: 337: 26.46
+	Hs
		851759 NEK4_HUMAN (918-1072): 1.43e-15: 84: 30.25		PCDGD_HUMAN (2-447): 1.53e-100: 337: 26.46
+	Hs
		851757 NEK4_HUMAN (918-1072): 1.43e-15: 84: 30.25		PCDBB_HUMAN (461-902): 1.73e-37: 153: 14.46