HitPredict

Interactor 1: NLK (Q9UBE8)
Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)
Gene: NLK

Interactor 2: TRPS1 (Q9UHF7)
Zinc finger transcription factor Trps1 (Tricho-rhino-phalangeal syndrome type I protein) (Zinc finger protein GC79)
Gene: TRPS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 23602568
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 527 Hs			1 1281
+	Hs
		659080 MK01_HUMAN (124-494): 8.01e-136: 399: 37.53		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		647704 MK03_HUMAN (110-496): 5.3e-135: 397: 35.73		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		658835 MK01_HUMAN (124-494): 8.01e-136: 399: 37.53		GATA4_HUMAN (870-1060): 3.74e-45: 171: 28.36
+	Mm
		570287 MK01_MOUSE (116-494): 5.23e-136: 399: 37.53		GATA1_MOUSE (804-1033): 5.18e-40: 155: 20.21
+	Hs
		620451 CDK2_HUMAN (135-433): 5.33e-139: 405: 35.55		GATA3_HUMAN (870-1017): 3.94e-36: 144: 27.03
+	Hs
		620296 CDK2_HUMAN (135-433): 5.33e-139: 405: 35.55		GATA2_HUMAN (821-1072): 2.62e-27: 119: 20.60
+	Hs
		620503 MK14_HUMAN (143-468): 5.29e-77: 248: 43.73		GATA3_HUMAN (870-1017): 3.94e-36: 144: 27.03