HitPredict

Interactor 1: PSMD1 (Q9V3P6)
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory complex subunit p110) (26S proteasome regulatory subunit RPN2)
Gene: Rpn2

Interactor 2: Q9V405 (Q9V405)
26S proteasome regulatory subunit 6B
Gene: Rpt3

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005838 - proteasome regulatory particle GO:0008540 - proteasome regulatory particle, base subcomplex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1020 Dm			1 413
+	At
		235425 PSD1A_ARATH (3-1017): 0: 1201: 45.72		PRS4A_ARATH (36-407): 2.45e-156: 450: 51.07
+	Dm
		874996 PSMD1_DROME (1-1004): 0: 1198: 100.00		PRS4_DROME (37-407): 9.23e-156: 448: 50.54
+	At
		1444857 PSD1B_ARATH (3-1017): 0: 1178: 44.96		PRS4A_ARATH (36-407): 2.45e-156: 450: 51.07
+	Dm
		198065 PSMD1_DROME (1-1004): 0: 1198: 100.00		PRS8_DROME (35-413): 1.63e-123: 365: 41.95
+	Dm
		1464104 PSMD1_DROME (1-1004): 0: 1198: 100.00		Q9W414_DROME (34-411): 1.17e-120: 357: 42.11
+	Hs
		851400 PSMD1_HUMAN (3-1001): 0: 1176: 60.30		PRS6B_HUMAN (1-413): 3.2e-128: 377: 86.20
+	Hs
		975490 PSMD1_HUMAN (3-1001): 0: 1176: 60.30		PRS10_HUMAN (30-411): 1.72e-122: 362: 40.63
+	Hs
		969030 PSMD1_HUMAN (3-1001): 0: 1176: 60.30		PRS8_HUMAN (35-413): 7.78e-119: 353: 42.22
+	Hs
		968792 PSMD1_HUMAN (3-1001): 0: 1176: 60.30		PRS4_HUMAN (37-407): 6.75e-115: 344: 49.87
+	Hs
		692 A0A087WW66_HUMAN (3-1001): 0: 1100: 57.50		PRS6B_HUMAN (1-413): 3.2e-128: 377: 86.20
+	Hs
		700 A0A087WW66_HUMAN (3-1001): 0: 1100: 57.50		PRS10_HUMAN (30-411): 1.72e-122: 362: 40.63
+	Hs
		699 A0A087WW66_HUMAN (3-1001): 0: 1100: 57.50		PRS8_HUMAN (35-413): 7.78e-119: 353: 42.22
+	Sp
		268014 RPN2_SCHPO (3-1017): 0: 1018: 42.27		PRS6B_SCHPO (27-413): 2.89e-139: 404: 74.29
+	Sp
		268018 RPN2_SCHPO (3-1017): 0: 1018: 42.27		PRS4_SCHPO (37-406): 4.04e-125: 370: 52.53
+	Sc
		740172 RPN2_YEAST (1-1016): 0: 950: 35.74		PRS4_YEAST (41-409): 2.62e-125: 370: 50.67
+	Sc
		740129 RPN2_YEAST (1-1016): 0: 950: 35.74		PRS6B_YEAST (34-413): 1.87e-122: 363: 72.85
+	Sc
		740209 RPN2_YEAST (1-1016): 0: 950: 35.74		PRS8_YEAST (35-408): 1.27e-122: 362: 40.91
+	Sc
		740197 RPN2_YEAST (1-1016): 0: 950: 35.74		PRS10_YEAST (8-413): 2.67e-117: 350: 38.54
+	Hs
		69435 PSMD2_HUMAN (9-812): 0: 757: 16.90		A8K2M0_HUMAN (1-413): 3.2e-128: 377: 86.20
+	Hs
		851303 PSMD2_HUMAN (9-812): 0: 757: 16.90		PRS6B_HUMAN (1-413): 3.2e-128: 377: 86.20