Interactor 1: DNM1L (O00429)
Dynamin-1-like protein (EC 3.6.5.5) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-like protein) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV) (Dynamin-related protein 1)
Gene: DNM1L
Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 0.60 | 0.731 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24282027, 22228096, 29541021, unassigned1853, 22639965, 23813973 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation, protein kinase assay |
| Interaction Type | physical association, association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0003924 - GTPase activity GO:0005096 - GTPase activator activity GO:0005525 - GTP binding GO:0005737 - cytoplasm GO:0005739 - mitochondrion and 14 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
