Protein: M3K10
Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)

Gene: M3K10, MAP3K10
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q02779

Gene Ontology (top 5):
GO:0003714 - transcription corepressor activity
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004706 - JUN kinase kinase kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1038574

M3K21
Mitogen-activated protein kinase kinase kinase 21

2

19

High-throughput

0.817

High

971424

1433E
14-3-3 protein epsilon

2

11

Small-scale

0.754

High

1038570

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

13

Small-scale

0.724

High

1038583

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

1

18

Small-scale

0.724

High

703544

MK01
Mitogen-activated protein kinase 1

1

18

Small-scale

0.710

High

853779

MK09
Mitogen-activated protein kinase 9

1

20

Small-scale

0.710

High

1038567

M3K10
Mitogen-activated protein kinase kinase kinase 10

1

16

Small-scale

0.710

High

840948

ABL2
Tyrosine-protein kinase ABL2

1

17

High-throughput

0.698

High

461375

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.691

High

468281

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.691

High

720195

UFO
Tyrosine-protein kinase receptor UFO

1

20

High-throughput

0.691

High

1038573

CDC37
Hsp90 co-chaperone Cdc37

1

10

High-throughput

0.691

High

955075

CDC42
Cell division control protein 42 homolog

1

20

Small-scale

0.680

High

988297

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

Small-scale

0.680

High

853882

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

20

Small-scale

0.647

High

1038569

DYN1
Dynamin-1

1

6

Small-scale

0.647

High

1038572

MK14
Mitogen-activated protein kinase 14

1

18

Small-scale

0.647

High

690923

1433T
14-3-3 protein theta

1

20

High-throughput

0.618

High

729762

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.618

High

730525

1433S
14-3-3 protein sigma

1

20

High-throughput

0.618

High

966212

1433G
14-3-3 protein gamma

1

20

High-throughput

0.618

High

990120

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.618

High

1006049

DLG4
Disks large homolog 4

1

12

Small-scale

0.618

High

1038568

1433F
14-3-3 protein eta

1

20

High-throughput

0.618

High

1014850

HPCA
Neuron-specific calcium-binding protein hippocalcin

2

13

Small-scale

0.611

High

1038577

KIFA3
Kinesin-associated protein 3

1

10

Small-scale

0.552

High

1038584

KIF3A
Kinesin-like protein KIF3A

1

7

Small-scale

0.552

High

1038571

NDF1
Neurogenic differentiation factor 1

1

0

Small-scale

0.549

High

834298

GARS
Glycine--tRNA ligase

1

1

High-throughput

0.541

High

1038575

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

5

High-throughput

0.536

High

1038576

MY18B
Unconventional myosin-XVIIIb

1

3

High-throughput

0.536

High

1038578

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

9

High-throughput

0.536

High

958624

CSN2
COP9 signalosome complex subunit 2

1

0

Small-scale

0.526

High

1038579

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.518

High

1038580

NP1L4
Nucleosome assembly protein 1-like 4

1

0

High-throughput

0.513

High

169520

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

7

Small-scale

0.501

High

1038581

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

14

Small-scale

0.501

High

789631

HPCL1
Hippocalcin-like protein 1

1

13

High-throughput

0.489

High

1038582

KIF17
Kinesin-like protein KIF17

1

7

Small-scale

0.481

High

843497

HD
Huntingtin

1

0

Small-scale

0.458

High

1025986

CLH1
Clathrin heavy chain 1

1

3

Small-scale

0.437

High

909428

NDUA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025