HitPredict

Interactor 1: FBLI1 (Q8WUP2)
Filamin-binding LIM protein 1 (FBLP-1) (Migfilin) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein)
Gene: FBLIM1

Interactor 2: EVL (Q9UI08)
Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like)
Gene: EVL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LIM~WH1
Common GO terms	GO:0001725 - stress fiber GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 373 Hs			1 416
+	Hs
		896592 FBLI1_HUMAN (1-373): 6.53e-89: 274: 100.00		VASP_HUMAN (1-412): 3.11e-57: 194: 41.59
+	Hs
		896599 LPP_HUMAN (7-367): 1.19e-73: 241: 27.39		VASP_HUMAN (1-412): 3.11e-57: 194: 41.59
+	Hs
		896658 LIMD1_HUMAN (4-371): 7.77e-71: 235: 28.21		VASP_HUMAN (1-412): 3.11e-57: 194: 41.59
+	Hs
		1331343 FBLI1_HUMAN (1-373): 6.53e-89: 274: 100.00		ENAH_HUMAN (94-415): 6.19e-30: 123: 32.24
+	Hs
		878416 PAXI_HUMAN (6-368): 3.71e-51: 181: 18.33		VASP_HUMAN (1-412): 3.11e-57: 194: 41.59
+	Hs
		1156240 ZYX_HUMAN (2-295): 5.58e-16: 81.1: 15.03		EVL_HUMAN (1-416): 9.35e-86: 269: 100.00
+	Hs
		359 ZYX_HUMAN (2-295): 5.58e-16: 81.1: 15.03		A0A075B6E5_HUMAN (1-151): 2.37e-72: 227: 57.96
+	Hs
		896537 ZYX_HUMAN (2-295): 5.58e-16: 81.1: 15.03		VASP_HUMAN (1-412): 3.11e-57: 194: 41.59
+	Dm
		1216728 Q5U0W6_DROME (238-373): 2.95e-28: 117: 25.36		ENA_DROME (2-386): 1.31e-40: 155: 24.17
+	Dm
		1301127 Q8I0G8_DROME (238-373): 2.47e-28: 117: 25.36		ENA_DROME (2-386): 1.31e-40: 155: 24.17
+	Hs
		1331347 AJUBA_HUMAN (237-372): 9.29e-20: 92.6: 24.65		ENAH_HUMAN (94-415): 6.19e-30: 123: 32.24
+	Hs
		1156152 ZYX_HUMAN (2-295): 5.58e-16: 81.1: 15.03		ENAH_HUMAN (94-415): 6.19e-30: 123: 32.24
+	Mm
		1041722 ZYX_MOUSE (2-298): 5.91e-15: 78: 14.24		ENAH_MOUSE (96-415): 5.2e-09: 60.4: 31.61