HitPredict

Interactor 1: A0A075B6E5 (A0A075B6E5)
ENAH actin regulator
Gene: ENAH

Interactor 2: ZYX (Q15942)
Zyxin (Zyxin-2)
Gene: ZYX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	LIM~WH1
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 572
+	Mm
		975400 ENAH_MOUSE (1-161): 1.42e-59: 201: 99.38		ZYX_MOUSE (1-572): 3.2e-62: 216: 85.02
+	Hs
		1080725 ENAH_HUMAN (1-161): 2.41e-49: 170: 87.58		ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00
+	Dm
		1210945 ENA_DROME (2-168): 6.11e-43: 155: 51.15		Q8I0G8_DROME (276-572): 3.5e-75: 249: 37.37
+	Dm
		1137155 ENA_DROME (2-168): 6.11e-43: 155: 51.15		Q5U0W6_DROME (276-569): 8.42e-74: 246: 37.08
+	Hs
		1237868 ENAH_HUMAN (1-161): 2.41e-49: 170: 87.58		FBLI1_HUMAN (252-572): 4.13e-67: 224: 29.61
+	Hs
		1080810 EVL_HUMAN (1-187): 2.68e-41: 146: 56.38		ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00
+	Hs
		840482 VASP_HUMAN (1-150): 1.38e-41: 146: 53.95		ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00
+	Hs
		840600 VASP_HUMAN (1-150): 1.38e-41: 146: 53.95		LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80
+	Hs
		1260462 EVL_HUMAN (1-187): 2.68e-41: 146: 56.38		FBLI1_HUMAN (252-572): 4.13e-67: 224: 29.61
+	Hs
		840535 VASP_HUMAN (1-150): 1.38e-41: 146: 53.95		FBLI1_HUMAN (252-572): 4.13e-67: 224: 29.61
+	Rn
		1101450 Q5XHX3_RAT (1-161): 6.5e-50: 171: 85.71		TES_RAT (294-571): 6.62e-27: 115: 15.36
+	Hs
		823356 VASP_HUMAN (1-150): 1.38e-41: 146: 53.95		PAXI_HUMAN (8-500): 3.72e-32: 132: 12.12
+	Hs
		1191615 SPRE1_HUMAN (2-193): 3.81e-54: 180: 27.40		TES_HUMAN (345-499): 3.83e-20: 95.1: 17.28
+	Hs
		1237898 ENAH_HUMAN (1-161): 2.41e-49: 170: 87.58		TES_HUMAN (345-499): 3.83e-20: 95.1: 17.28
+	Hs
		1237872 ENAH_HUMAN (1-161): 2.41e-49: 170: 87.58		AJUBA_HUMAN (9-499): 2.93e-13: 74.3: 11.33
+	Hs
		1190444 SPRE1_HUMAN (2-193): 3.81e-54: 180: 27.40		LIMS2_HUMAN (384-544): 8.75e-10: 62.4: 27.55
+	Hs
		1355072 EVL_HUMAN (1-187): 2.68e-41: 146: 56.38		TES_HUMAN (345-499): 3.83e-20: 95.1: 17.28
+	Hs
		840599 VASP_HUMAN (1-150): 1.38e-41: 146: 53.95		TES_HUMAN (345-499): 3.83e-20: 95.1: 17.28
+	Hs
		840541 VASP_HUMAN (1-150): 1.38e-41: 146: 53.95		LPP_HUMAN (4-495): 1.9e-13: 75.1: 13.92