HitPredict

Interactor 1: MYO6 (Q9UM54)
Unconventional myosin-VI (Unconventional myosin-6)
Gene: MYO6

Interactor 2: MTCL1 (Q9Y4B5)
Microtubule cross-linking factor 1 (Coiled-coil domain-containing protein 165) (PAR-1-interacting protein) (SOGA family member 2)
Gene: MTCL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29467281
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1294 Hs			1 1905
+	Hs
		725068 MYO6_HUMAN (1-1294): 0: 1083: 100.00		MYH9_HUMAN (171-636): 9.75e-11: 69.3: 10.04
+	Dm
		968555 MYS9_DROME (1-1265): 0: 908: 48.28		CL190_DROME (3-1530): 1.26e-59: 229: 10.93
+	Dm
		1303383 MYO7A_DROME (1-951): 0: 891: 30.83		MYSN_DROME (333-1288): 1.78e-16: 88.4: 18.89
+	Hs
		725035 MYO5C_HUMAN (772-1230): 2.22e-24: 113: 9.42		MYH9_HUMAN (171-636): 9.75e-11: 69.3: 10.04
+	Hs
		522585 MYH7_HUMAN (766-1261): 3.15e-15: 83.6: 11.01		MYH7_HUMAN (157-813): 2.43e-17: 91.3: 10.38
+	Hs
		522657 MYH7_HUMAN (766-1261): 3.15e-15: 83.6: 11.01		MYH4_HUMAN (194-846): 3.07e-17: 90.9: 10.84
+	Rn
		361106 MYH6_RAT (759-1235): 5.4e-16: 86.3: 12.75		MYH6_RAT (240-707): 1.2e-13: 79: 11.92
+	Hs
		502901 MYH6_HUMAN (760-1113): 5.54e-10: 66.2: 18.89		MYH3_HUMAN (172-837): 1.14e-17: 92.4: 13.13
+	Hs
		528356 MYH6_HUMAN (760-1113): 5.54e-10: 66.2: 18.89		MYH6_HUMAN (161-848): 4.68e-17: 90.1: 10.65
+	Hs
		724687 MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70		MYH10_HUMAN (127-797): 1.09e-16: 89: 10.88
+	Hs
		725095 MYH10_HUMAN (762-1135): 7.28e-10: 65.8: 15.54		MYH10_HUMAN (127-797): 1.09e-16: 89: 10.88
+	Hs
		725097 MYH10_HUMAN (762-1135): 7.28e-10: 65.8: 15.54		MYH11_HUMAN (1036-1546): 1.17e-15: 85.9: 8.86
+	Hs
		724686 MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70		MYH9_HUMAN (171-636): 9.75e-11: 69.3: 10.04
+	Hs
		725065 MYO5B_HUMAN (1016-1294): 4.73e-09: 63.4: 12.41		MYH9_HUMAN (171-636): 9.75e-11: 69.3: 10.04
+	Hs
		725086 MYO5A_HUMAN (595-1063): 4.98e-09: 63: 10.72		MYH9_HUMAN (171-636): 9.75e-11: 69.3: 10.04
+	Hs
		724839 MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70		PLEC_HUMAN (321-1278): 1.45e-09: 65.7: 16.15