HitPredict

Interactor 1: PHIP (Q8WWQ0)
PH-interacting protein (PHIP) (DDB1- and CUL4-associated factor 14) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)
Gene: PHIP

Interactor 2: HDA11 (Q96DB2)
Histone deacetylase 11 (HD11) (EC 3.5.1.98)
Gene: HDAC11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23752268
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1821 Hs			1 347
+	Mm
		107148 F8VQ93_MOUSE (1-1821): 0: 1534: 94.89		HDAC4_MOUSE (1-341): 6.6e-129: 396: 21.60
+	Mm
		1240128 PHIP_MOUSE (1-1821): 0: 1532: 94.78		HDAC4_MOUSE (1-341): 6.6e-129: 396: 21.60
+	Hs
		1359715 PHIP_HUMAN (1-1821): 0: 1532: 100.00		HDAC6_HUMAN (18-346): 8.72e-95: 307: 21.31
+	Hs
		261406 TBL1X_HUMAN (10-302): 2.8e-59: 217: 13.58		HDAC1_HUMAN (13-330): 8.91e-140: 407: 22.89
+	Hs
		261390 TBL1X_HUMAN (10-302): 2.8e-59: 217: 13.58		HDAC4_HUMAN (1-341): 1.28e-127: 393: 20.53
+	Hs
		1368034 FBXW7_HUMAN (294-643): 1.42e-58: 218: 17.61		HDAC2_HUMAN (13-330): 4.92e-128: 376: 22.89
+	Hs
		261430 TBL1X_HUMAN (10-302): 2.8e-59: 217: 13.58		HDAC2_HUMAN (13-330): 4.92e-128: 376: 22.89
+	Hs
		188125 TBL1X_HUMAN (10-302): 2.8e-59: 217: 13.58		HDAC3_HUMAN (14-340): 3.71e-128: 375: 20.47
+	Hs
		1356752 FBXW7_HUMAN (294-643): 1.42e-58: 218: 17.61		HDAC7_HUMAN (13-344): 1.92e-121: 373: 19.89
+	Hs
		261429 TBL1X_HUMAN (10-302): 2.8e-59: 217: 13.58		HDAC7_HUMAN (13-344): 1.92e-121: 373: 19.89
+	Mm
		1240081 PB1_MOUSE (1122-1664): 1.85e-45: 183: 15.89		HDAC4_MOUSE (1-341): 6.6e-129: 396: 21.60
+	Mm
		107166 F8VQD1_MOUSE (1122-1784): 7.63e-44: 178: 14.71		HDAC4_MOUSE (1-341): 6.6e-129: 396: 21.60
+	Hs
		964922 WDR5_HUMAN (458-685): 7.4e-40: 153: 11.57		HDAC1_HUMAN (13-330): 8.91e-140: 407: 22.89
+	Hs
		1356773 BRWD1_HUMAN (1-298): 2.93e-43: 176: 16.06		HDAC7_HUMAN (13-344): 1.92e-121: 373: 19.89
+	Hs
		188353 TBL1Y_HUMAN (342-650): 1.28e-43: 170: 16.43		HDAC3_HUMAN (14-340): 3.71e-128: 375: 20.47
+	Hs
		965127 WDR5_HUMAN (458-685): 7.4e-40: 153: 11.57		HDAC2_HUMAN (13-330): 4.92e-128: 376: 22.89
+	Hs
		188229 WDR5_HUMAN (458-685): 7.4e-40: 153: 11.57		HDAC3_HUMAN (14-340): 3.71e-128: 375: 20.47
+	Dm
		1302301 EBI_DROME (1-173): 1.91e-34: 145: 5.46		Q8I9J6_DROME (2-340): 7.29e-121: 378: 21.15
+	Dm
		1269416 EBI_DROME (1-173): 1.91e-34: 145: 5.46		Q7KTS4_DROME (14-334): 2.08e-124: 366: 21.24
+	Dm
		1377789 EBI_DROME (1-173): 1.91e-34: 145: 5.46		Q9VNC2_DROME (14-334): 3.93e-123: 362: 21.24