HitPredict

Interactor 1: WARTS (Q9VA38)
Serine/threonine-protein kinase Warts (EC 2.7.11.1)
Gene: wts

Interactor 2: KIBRA (Q9VFG8)
Protein kibra
Gene: KIBRA

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33555257
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007298 - border follicle cell migration GO:0043065 - positive regulation of apoptotic process GO:0045463 - R8 cell development GO:0045464 - R8 cell fate specification GO:0060253 - negative regulation of glial cell proliferation and 1 others more... GO:0106037 - apicomedial cortex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1105 Dm			1 1288
+	Hs
		1149656 LATS2_HUMAN (117-1101): 0: 570: 39.52		WWC2_HUMAN (45-1156): 8.51e-166: 528: 28.91
+	Hs
		1344970 LATS2_HUMAN (117-1101): 0: 570: 39.52		WWC3_HUMAN (50-1156): 2.59e-159: 511: 28.36
+	Hs
		325775 LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59		WWC2_HUMAN (45-1156): 8.51e-166: 528: 28.91
+	Hs
		1220087 LATS2_HUMAN (117-1101): 0: 570: 39.52		KIBRA_HUMAN (52-1156): 3.02e-150: 484: 28.43
+	Hs
		325797 LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59		KIBRA_HUMAN (52-1156): 3.02e-150: 484: 28.43
+	Hs
		325898 LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59		SMUF1_HUMAN (25-238): 4.74e-56: 211: 18.60
+	Hs
		1300675 LATS2_HUMAN (117-1101): 0: 570: 39.52		MAGI1_HUMAN (50-141): 6.42e-35: 147: 36.54
+	Hs
		325894 LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59		SMUF2_HUMAN (4-238): 2.8e-47: 184: 16.79
+	Hs
		808960 LATS2_HUMAN (117-1101): 0: 570: 39.52		YAP1_HUMAN (38-152): 2.99e-34: 140: 29.13
+	Hs
		325772 LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59		MAGI3_HUMAN (32-153): 1.41e-38: 159: 37.71
+	Hs
		325859 LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59		MAGI1_HUMAN (50-141): 6.42e-35: 147: 36.54
+	Hs
		325656 LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59		YAP1_HUMAN (38-152): 2.99e-34: 140: 29.13
+	Hs
		325853 LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59		ITCH_HUMAN (47-162): 8.77e-30: 130: 28.21
+	Hs
		125071 LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59		WWP2_HUMAN (34-200): 2.43e-29: 128: 23.95
+	Hs
		808286 LATS2_HUMAN (117-1101): 0: 570: 39.52		NEDD4_HUMAN (2-217): 1.44e-15: 84.6: 17.51
+	Hs
		325886 LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59		WWP1_HUMAN (9-176): 1.4e-22: 106: 23.81
+	Hs
		325914 LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59		WWOX_HUMAN (48-134): 3.39e-23: 105: 32.18
+	Hs
		325655 LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59		NEDD4_HUMAN (2-217): 1.44e-15: 84.6: 17.51
+	Hs
		325608 LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59		MYH1_HUMAN (108-618): 1.03e-11: 72.2: 7.97
+	Hs
		325935 LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59		MYH2_HUMAN (108-618): 1.08e-10: 68.7: 7.59