HitPredict

Interactor 1: Q9VBI3 (Q9VBI3)
Charged multivesicular body protein 2a (Chromatin-modifying protein 2a)
Gene: Vps2

Interactor 2: CHMP5 (Q9VVI9)
Charged multivesicular body protein 5 (Vacuolar protein-sorting-associated protein 60)
Gene: Vps60

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Snf7~Snf7
Common GO terms	GO:0000815 - ESCRT III complex GO:0005771 - multivesicular body GO:0015031 - protein transport GO:0032509 - endosome transport via multivesicular body sorting pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 256 Dm			1 226
+	Hs
		208864 CHM2A_HUMAN (1-190): 1.75e-41: 143: 77.90		CHMP5_HUMAN (1-222): 5.18e-43: 146: 63.06
+	Ce
		1090380 Q9U2F6_CAEEL (1-256): 7.98e-48: 160: 63.28		Q18886_CAEEL (2-218): 3.9e-34: 123: 22.94
+	Dm
		1249815 Q9VBI3_DROME (1-256): 2.69e-43: 149: 100.00		CHM4_DROME (7-222): 3.8e-31: 115: 24.42
+	At
		1013164 VPS2A_ARATH (1-255): 6.41e-47: 157: 45.49		VPS2B_ARATH (7-190): 1.33e-26: 103: 16.85
+	Dm
		1362009 Q9VBI3_DROME (1-256): 2.69e-43: 149: 100.00		Q9VN02_DROME (4-219): 1.39e-28: 109: 12.96
+	Hs
		208872 CHM2A_HUMAN (1-190): 1.75e-41: 143: 77.90		CHMP3_HUMAN (4-225): 3.84e-30: 112: 15.77
+	At
		98408 F4JXR3_ARATH (1-229): 1.03e-44: 153: 14.55		VP322_ARATH (1-223): 2.66e-26: 102: 26.67
+	Sc
		732840 DID4_YEAST (2-256): 6.75e-41: 142: 39.45		DID4_YEAST (7-225): 2.12e-29: 111: 13.84
+	Hs
		92838 E9PSI1_HUMAN (1-195): 3e-40: 149: 16.04		CHM4B_HUMAN (15-214): 1.97e-26: 103: 23.27
+	At
		287073 VP601_ARATH (1-229): 2.46e-42: 146: 16.46		VP321_ARATH (1-223): 5.43e-27: 104: 27.35
+	At
		1013158 VP601_ARATH (1-229): 2.46e-42: 146: 16.46		VPS2B_ARATH (7-190): 1.33e-26: 103: 16.85
+	At
		1276045 VPS2C_ARATH (3-212): 1.71e-42: 145: 30.48		VP202_ARATH (1-213): 9.33e-27: 104: 19.01
+	Dm
		1362010 Q9VBI3_DROME (1-256): 2.69e-43: 149: 100.00		Q9VRJ5_DROME (2-211): 2.4e-25: 100: 12.86
+	At
		287069 VPS2C_ARATH (3-212): 1.71e-42: 145: 30.48		VP321_ARATH (1-223): 5.43e-27: 104: 27.35
+	At
		1339085 VP601_ARATH (1-229): 2.46e-42: 146: 16.46		VP322_ARATH (1-223): 2.66e-26: 102: 26.67
+	Hs
		208801 CHM2A_HUMAN (1-190): 1.75e-41: 143: 77.90		CHM2A_HUMAN (7-224): 1.77e-27: 105: 16.97
+	At
		1276050 VPS2C_ARATH (3-212): 1.71e-42: 145: 30.48		VP322_ARATH (1-223): 2.66e-26: 102: 26.67
+	Hs
		208860 CHM2A_HUMAN (1-190): 1.75e-41: 143: 77.90		CHM4B_HUMAN (15-214): 1.97e-26: 103: 23.27
+	At
		1209623 VPS2C_ARATH (3-212): 1.71e-42: 145: 30.48		VP201_ARATH (1-202): 2.96e-25: 100: 19.71
+	Sc
		732845 DID4_YEAST (2-256): 6.75e-41: 142: 39.45		SNF7_YEAST (3-212): 4.36e-25: 100: 24.41