Interactor 1: AIR2 (O01427)
Aurora/IPL1-related protein kinase 2 (EC 2.7.11.1) (Serine/threonine-protein kinase aurora-B)
Gene: air-2

Interactor 2: TLK1 (P34314)
Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled-like kinase 1)
Gene: tlk-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.756

The method score is based on:

Property Details
Experiments 15916946
Identification Methods affinity chromatography technology, enzymatic study, anti bait coimmunoprecipitation, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0007059 - chromosome segregation
GO:0016310 - phosphorylation
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 305
Ce

1 965
+ Hs
+ Rn
+ Rn
+ At
+ At
+ Hs
+ Hs
+ At
+ At
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024