HitPredict

Interactor 1: Q9VDS9 (Q9VDS9)
Apoptotic signal-regulating kinase 1, isoform C (EC 2.7.11.25)
Gene: Ask1

Interactor 2: Q9VH81 (Q9VH81)
protein-serine/threonine phosphatase (EC 3.1.3.16)
Gene: PpD3

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25294943
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1363 Dm			1 520
+	Hs
		858663 M3K5_HUMAN (3-1300): 0: 1174: 39.89		PPP5_HUMAN (38-516): 0: 548: 59.50
+	Rn
		858690 AKT3_RAT (476-875): 8.08e-120: 384: 20.72		PPP5_RAT (38-516): 0: 546: 59.08
+	Hs
		647866 MARK3_HUMAN (540-1261): 1.46e-132: 428: 13.88		PP2AB_HUMAN (205-503): 2.98e-164: 469: 38.33
+	Mm
		915321 TNIK_MOUSE (585-1222): 2.98e-123: 417: 18.11		PP2AB_MOUSE (205-503): 2.98e-164: 469: 38.33
+	Mm
		906234 TNIK_MOUSE (585-1222): 2.98e-123: 417: 18.11		PP1A_MOUSE (219-503): 1.38e-159: 458: 38.81
+	Mm
		926532 TNIK_MOUSE (585-1222): 2.98e-123: 417: 18.11		PP1G_MOUSE (219-505): 4.16e-159: 456: 38.54
+	Hs
		851427 NEK4_HUMAN (585-1241): 1.16e-117: 390: 18.81		PP2AB_HUMAN (205-503): 2.98e-164: 469: 38.33
+	Dm
		619883 AKT1_DROME (473-895): 9.93e-122: 394: 20.90		PP2A_DROME (205-503): 5.85e-162: 463: 37.33
+	Hs
		931045 AKT3_HUMAN (476-884): 6.71e-122: 389: 21.31		PP2AA_HUMAN (205-503): 3.43e-163: 466: 38.33
+	Hs
		737664 NEK4_HUMAN (585-1241): 1.16e-117: 390: 18.81		PP1G_HUMAN (219-505): 5.83e-159: 456: 38.54
+	Hs
		331249 CHK2_HUMAN (554-867): 1.28e-97: 325: 28.66		PP2AA_HUMAN (205-503): 3.43e-163: 466: 38.33
+	Hs
		906441 PAK2_HUMAN (584-844): 6.72e-99: 328: 32.57		PP1B_HUMAN (218-515): 2.36e-160: 460: 36.79
+	Hs
		930841 KCC1A_HUMAN (583-945): 5.78e-98: 320: 25.34		PP2AA_HUMAN (205-503): 3.43e-163: 466: 38.33
+	Hs
		905867 PAK2_HUMAN (584-844): 6.72e-99: 328: 32.57		PP1A_HUMAN (219-503): 3.53e-159: 457: 38.81
+	Hs
		930968 M3K3_HUMAN (587-844): 5.81e-45: 175: 42.75		PP2AA_HUMAN (205-503): 3.43e-163: 466: 38.33
+	Hs
		906105 M3K3_HUMAN (587-844): 5.81e-45: 175: 42.75		PP1A_HUMAN (219-503): 3.53e-159: 457: 38.81
+	Hs
		738002 M3K3_HUMAN (587-844): 5.81e-45: 175: 42.75		PP1G_HUMAN (219-505): 5.83e-159: 456: 38.54
+	Hs
		682162 AKT2_HUMAN (368-497): 6.46e-17: 87.6: 14.82		PP2AA_HUMAN (205-503): 3.43e-163: 466: 38.33
+	Hs
		681767 AKT1_HUMAN (368-511): 5.34e-16: 84.5: 11.41		PP1A_HUMAN (219-503): 3.53e-159: 457: 38.81
+	Hs
		681698 AKT1_HUMAN (368-511): 5.34e-16: 84.5: 11.41		PP1G_HUMAN (219-505): 5.83e-159: 456: 38.54