Interactor 1: EDEM1 (Q92611)
ER degradation-enhancing alpha-mannosidase-like protein 1
Gene: EDEM1
Interactor 2: MA1B1 (Q9UKM7)
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (ER mannosidase 1) (ERMan1) (Man9GlcNAc2-specific-processing alpha-mannosidase) (Mannosidase alpha class 1B member 1)
Gene: MAN1B1
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32423001 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Glyco_hydro_47~Glyco_hydro_47 |
| Common GO terms | GO:0004571 - mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0005509 - calcium ion binding GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0036503 - ERAD pathway and 2 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
