Interactor 1: EDEM2 (Q9BV94)
ER degradation-enhancing alpha-mannosidase-like protein 2
Gene: EDEM2
Interactor 2: EDEM3 (Q9BZQ6)
ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)
Gene: EDEM3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.54 | 1.00 | 0.737 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28366632, unassigned3799 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Glyco_hydro_47~Glyco_hydro_47 |
| Common GO terms | GO:0004571 - mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0005509 - calcium ion binding GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0005975 - carbohydrate metabolic process and 6 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
