HitPredict

Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: ELAV1 (Q15717)
ELAV-like protein 1 (Hu-antigen R) (HuR)
Gene: ELAVL1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23772036
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0048255 - mRNA stabilization
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 557 Hs			1 326
+	Hs
		1090660 TRAF2_HUMAN (28-554): 5.57e-103: 321: 31.84		ELAV1_HUMAN (1-326): 6.43e-89: 271: 100.00
+	Hs
		623358 RO52_HUMAN (32-468): 7.46e-77: 252: 11.16		ELAV1_HUMAN (1-326): 6.43e-89: 271: 100.00
+	Hs
		1125113 TRI25_HUMAN (38-387): 1.07e-43: 166: 15.43		ELAV1_HUMAN (1-326): 6.43e-89: 271: 100.00
+	Hs
		1152625 TRI31_HUMAN (34-365): 4.86e-41: 155: 16.42		ELAV1_HUMAN (1-326): 6.43e-89: 271: 100.00
+	Hs
		1197175 TRI11_HUMAN (32-468): 5.66e-74: 244: 12.50		PAP1L_HUMAN (6-248): 1.06e-46: 168: 19.16
+	Dm
		620710 Q960H6_DROME (124-550): 1.27e-65: 222: 20.05		SXL_DROME (1-199): 2.38e-54: 182: 43.72
+	Dm
		620742 Q9VXG5_DROME (153-550): 7.68e-61: 207: 19.28		SXL_DROME (1-199): 2.38e-54: 182: 43.72
+	Hs
		550542 TRAF6_HUMAN (21-551): 7.73e-81: 264: 22.02		PABP1_HUMAN (234-325): 6.64e-19: 89.3: 19.57
+	Hs
		550115 RO52_HUMAN (32-468): 7.46e-77: 252: 11.16		PABP1_HUMAN (234-325): 6.64e-19: 89.3: 19.57
+	Hs
		623537 RO52_HUMAN (32-468): 7.46e-77: 252: 11.16		PABP3_HUMAN (234-325): 1.19e-16: 82.3: 17.39
+	Hs
		1102057 TRI11_HUMAN (32-468): 5.66e-74: 244: 12.50		PABP4_HUMAN (234-325): 1.05e-18: 88.5: 20.65
+	Hs
		550283 TRI25_HUMAN (38-387): 1.07e-43: 166: 15.43		PABP1_HUMAN (234-325): 6.64e-19: 89.3: 19.57
+	Hs
		1101953 TRI25_HUMAN (38-387): 1.07e-43: 166: 15.43		PABP4_HUMAN (234-325): 1.05e-18: 88.5: 20.65
+	Hs
		550455 TRI31_HUMAN (34-365): 4.86e-41: 155: 16.42		PABP1_HUMAN (234-325): 6.64e-19: 89.3: 19.57
+	Hs
		1102085 TRI31_HUMAN (34-365): 4.86e-41: 155: 16.42		PABP4_HUMAN (234-325): 1.05e-18: 88.5: 20.65
+	Hs
		506135 RN151_HUMAN (35-176): 1.13e-40: 149: 30.07		PAB4L_HUMAN (20-184): 3.04e-12: 68.6: 28.42
+	Hs
		686650 RNF41_HUMAN (30-156): 3.91e-25: 108: 27.82		ELAV4_HUMAN (194-322): 5.18e-21: 94.3: 20.93