HitPredict

Interactor 1: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Interactor 2: PHX2B (Q99453)
Paired mesoderm homeobox protein 2B (Neuroblastoma Phox) (NBPhox) (PHOX2B homeodomain protein) (Paired-like homeobox 2B)
Gene: PHOX2B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19191321
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2442 Hs			1 314
+	Hs
		942458 CBP_HUMAN (1-2442): 0: 1096: 100.00		GSC_HUMAN (46-194): 5.99e-39: 139: 38.56
+	Hs
		662260 CBP_HUMAN (1-2442): 0: 1096: 100.00		PAX7_HUMAN (81-312): 4.38e-34: 132: 29.29
+	Hs
		210074 CBP_HUMAN (1-2442): 0: 1096: 100.00		CRX_HUMAN (90-299): 1.34e-34: 129: 32.23
+	Hs
		165156 CBP_HUMAN (1-2442): 0: 1096: 100.00		PHX2A_HUMAN (4-218): 3.16e-33: 125: 58.80
+	Hs
		685291 CBP_HUMAN (1-2442): 0: 1096: 100.00		PAX6_HUMAN (37-302): 2.27e-31: 123: 24.35
+	Dm
		122014 M9PH39_DROME (480-2357): 0: 819: 35.44		Q9W1H7_DROME (4-199): 4.45e-35: 128: 33.33
+	Hs
		210148 TRI33_HUMAN (614-1207): 1.09e-36: 154: 13.64		CRX_HUMAN (90-299): 1.34e-34: 129: 32.23
+	Hs
		180622 TIF1A_HUMAN (667-1202): 2.18e-34: 147: 17.97		CRX_HUMAN (90-299): 1.34e-34: 129: 32.23
+	Hs
		180746 TIF1A_HUMAN (667-1202): 2.18e-34: 147: 17.97		LHX1_HUMAN (50-313): 3.62e-33: 128: 21.72
+	Hs
		180711 TIF1A_HUMAN (667-1202): 2.18e-34: 147: 17.97		PAX6_HUMAN (37-302): 2.27e-31: 123: 24.35
+	Hs
		180751 TIF1A_HUMAN (667-1202): 2.18e-34: 147: 17.97		LHX2_HUMAN (4-231): 6.57e-31: 121: 20.18
+	Hs
		210041 PB1_HUMAN (1040-1195): 4.73e-12: 74.4: 19.87		CRX_HUMAN (90-299): 1.34e-34: 129: 32.23
+	Hs
		662289 CHD7_HUMAN (105-479): 4.97e-11: 71: 9.19		PAX7_HUMAN (81-312): 4.38e-34: 132: 29.29
+	Hs
		877528 PB1_HUMAN (1040-1195): 4.73e-12: 74.4: 19.87		LHX1_HUMAN (50-313): 3.62e-33: 128: 21.72
+	Hs
		210134 CHD7_HUMAN (105-479): 4.97e-11: 71: 9.19		CRX_HUMAN (90-299): 1.34e-34: 129: 32.23
+	Hs
		877571 CHD7_HUMAN (105-479): 4.97e-11: 71: 9.19		LHX1_HUMAN (50-313): 3.62e-33: 128: 21.72
+	Hs
		685251 PB1_HUMAN (1040-1195): 4.73e-12: 74.4: 19.87		PAX6_HUMAN (37-302): 2.27e-31: 123: 24.35
+	Hs
		895745 PB1_HUMAN (1040-1195): 4.73e-12: 74.4: 19.87		LHX2_HUMAN (4-231): 6.57e-31: 121: 20.18
+	Hs
		685368 CHD7_HUMAN (105-479): 4.97e-11: 71: 9.19		PAX6_HUMAN (37-302): 2.27e-31: 123: 24.35
+	Hs
		895809 CHD7_HUMAN (105-479): 4.97e-11: 71: 9.19		LHX2_HUMAN (4-231): 6.57e-31: 121: 20.18