HitPredict

Interactor 1: CEAM8 (P31997)
Carcinoembryonic antigen-related cell adhesion molecule 8 (CD67 antigen) (Carcinoembryonic antigen CGM6) (Non-specific cross-reacting antigen NCA-95) (CD antigen CD66b)
Gene: CEACAM8

Interactor 2: FREM2 (Q5SZK8)
FRAS1-related extracellular matrix protein 2 (ECM3 homolog)
Gene: FREM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 349 Hs			1 3169
+	Hs
		1132304 PSG8_HUMAN (3-326): 9.75e-47: 165: 37.81		FREM2_HUMAN (1-3169): 0: 2875: 100.00
+	Hs
		685259 CEAM8_HUMAN (1-349): 3.78e-78: 245: 100.00		FAT4_HUMAN (208-1746): 0: 661: 11.21
+	Hs
		1167041 PSG8_HUMAN (3-326): 9.75e-47: 165: 37.81		FAT4_HUMAN (208-1746): 0: 661: 11.21
+	Hs
		509876 PSG1_HUMAN (49-319): 7.58e-45: 160: 42.44		FAT3_HUMAN (92-1676): 3.38e-176: 615: 11.47
+	Hs
		685240 CEAM8_HUMAN (1-349): 3.78e-78: 245: 100.00		FAT1_HUMAN (1072-2628): 6.04e-149: 526: 10.83
+	Hs
		1108786 CEA21_HUMAN (149-340): 1.19e-15: 78.3: 19.03		FAT4_HUMAN (208-1746): 0: 661: 11.21
+	Hs
		1055023 PSG8_HUMAN (3-326): 9.75e-47: 165: 37.81		FAT1_HUMAN (1072-2628): 6.04e-149: 526: 10.83
+	Hs
		1336515 PSG8_HUMAN (3-326): 9.75e-47: 165: 37.81		CELR2_HUMAN (31-1075): 7.48e-97: 354: 12.65
+	Hs
		685264 CEAM8_HUMAN (1-349): 3.78e-78: 245: 100.00		FRAS1_HUMAN (1065-2550): 1.86e-50: 201: 15.01
+	Hs
		1108811 CEA21_HUMAN (149-340): 1.19e-15: 78.3: 19.03		CELR2_HUMAN (31-1075): 7.48e-97: 354: 12.65
+	Hs
		685294 CEAM8_HUMAN (1-349): 3.78e-78: 245: 100.00		CELR3_HUMAN (55-554): 1.01e-44: 182: 11.33
+	Hs
		685278 CEAM8_HUMAN (1-349): 3.78e-78: 245: 100.00		AGRV1_HUMAN (525-2323): 9.4e-31: 136: 14.81
+	Hs
		1204968 PSG8_HUMAN (3-326): 9.75e-47: 165: 37.81		FRAS1_HUMAN (1065-2550): 1.86e-50: 201: 15.01
+	Hs
		1348655 PSG8_HUMAN (3-326): 9.75e-47: 165: 37.81		CELR3_HUMAN (55-554): 1.01e-44: 182: 11.33
+	Hs
		509884 PSG1_HUMAN (49-319): 7.58e-45: 160: 42.44		CELR3_HUMAN (55-554): 1.01e-44: 182: 11.33
+	Hs
		1263696 PSG8_HUMAN (3-326): 9.75e-47: 165: 37.81		AGRV1_HUMAN (525-2323): 9.4e-31: 136: 14.81
+	Hs
		962533 PSG9_HUMAN (7-238): 1.47e-16: 82.2: 17.45		CELR3_HUMAN (55-554): 1.01e-44: 182: 11.33