Interactor 1: CLD5 (O00501)
Claudin-5 (Transmembrane protein deleted in VCFS) (TMDVCF)
Gene: CLDN5
Interactor 2: PMP22 (Q01453)
Peripheral myelin protein 22 (PMP-22) (Growth arrest-specific protein 3) (GAS-3)
Gene: PMP22
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.61 | 1.00 | 0.783 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, unassigned1304 |
| Identification Methods | two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PMP22_Claudin~PMP22_Claudin |
| Common GO terms | GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
