Protein: PMP22
Peripheral myelin protein 22 (PMP-22) (Growth arrest-specific protein 3) (GAS-3)

Gene: PMP22
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q01453

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0005923 - bicellular tight junction
GO:0006915 - apoptotic process
GO:0007268 - chemical synaptic transmission
GO:0007422 - peripheral nervous system development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

138557

CLD5
Claudin-5

2

5

High-throughput

0.783

High

942272

CLD6
Claudin-6

2

5

High-throughput

0.783

High

942406

CLD18
Claudin-18

2

5

High-throughput

0.783

High

1030389

SCN3B
Sodium channel regulatory subunit beta-3

2

4

High-throughput

0.783

High

820597

CEAM3
Cell adhesion molecule CEACAM3

2

0

High-throughput

0.742

High

932682

EMP1
Epithelial membrane protein 1

2

0

High-throughput

0.742

High

688549

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

3

7

High-throughput

0.675

High

1030381

SMIM3
Small integral membrane protein 3

4

2

High-throughput

0.647

High

669810

MYP0
Myelin protein P0

1

4

Small-scale

0.618

High

194688

FFAR2
Free fatty acid receptor 2

2

7

High-throughput

0.606

High

349628

TSN12
Tetraspanin-12

2

4

High-throughput

0.606

High

455964

ASGR2
Asialoglycoprotein receptor 2

2

3

High-throughput

0.606

High

485971

CD3G
T-cell surface glycoprotein CD3 gamma chain

2

1

High-throughput

0.606

High

622045

CD53
Leukocyte surface antigen CD53

2

4

High-throughput

0.606

High

690236

STOM
Stomatin

2

1

High-throughput

0.606

High

770845

OPRM
Mu-type opioid receptor

2

3

High-throughput

0.606

High

800285

INGR2
Interferon gamma receptor 2

2

1

High-throughput

0.606

High

870711

CXA8
Gap junction alpha-8 protein

2

2

High-throughput

0.606

High

1030354

CD69
Early activation antigen CD69

2

7

High-throughput

0.606

High

1030374

EDA
Ectodysplasin-A

2

2

High-throughput

0.606

High

1030380

GPR61
G-protein coupled receptor 61

2

2

High-throughput

0.606

High

1030382

MS4A7
Membrane-spanning 4-domains subfamily A member 7

2

2

High-throughput

0.606

High

1030390

GPC5D
G-protein coupled receptor family C group 5 member D

2

1

High-throughput

0.606

High

194820

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

2

0

High-throughput

0.580

High

292617

RENR
Renin receptor

2

0

High-throughput

0.580

High

726651

SDC4
Syndecan-4

2

0

High-throughput

0.580

High

870041

KCNJ6
G protein-activated inward rectifier potassium channel 2

2

0

High-throughput

0.580

High

1030362

CC50B
Cell cycle control protein 50B

2

0

High-throughput

0.580

High

1030365

F209A
Protein FAM209A

2

0

High-throughput

0.580

High

1030371

SYT2
Synaptotagmin-2

2

0

High-throughput

0.580

High

1030383

S38A1
Sodium-coupled neutral amino acid symporter 1

2

0

High-throughput

0.580

High

331468

APOL3
Apolipoprotein L3

2

1

High-throughput

0.553

High

939486

FCGRN
IgG receptor FcRn large subunit p51

2

1

High-throughput

0.553

High

1030355

PDZ1I
PDZK1-interacting protein 1

2

1

High-throughput

0.553

High

1030359

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

1

High-throughput

0.553

High

1030361

CL12B
C-type lectin domain family 12 member B

2

7

High-throughput

0.553

High

1030364

AR13B
ADP-ribosylation factor-like protein 13B

2

1

High-throughput

0.553

High

1030368

CLC14
C-type lectin domain family 14 member A

2

3

High-throughput

0.553

High

1030375

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

3

High-throughput

0.553

High

1030376

T4S18
Transmembrane 4 L6 family member 18

2

2

High-throughput

0.553

High

1030377

T4S19
Transmembrane 4 L6 family member 19

2

2

High-throughput

0.553

High

1030379

TLCD4
TLC domain-containing protein 4

2

1

High-throughput

0.553

High

1030386

SACA1
Sperm acrosome membrane-associated protein 1

2

2

High-throughput

0.553

High

1030392

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

2

High-throughput

0.553

High

230302

CREB3
Cyclic AMP-responsive element-binding protein 3

1

3

High-throughput

0.523

High

193405

GPR42
G-protein coupled receptor 42

1

8

High-throughput

0.515

High

832621

AQP2
Aquaporin-2

1

3

High-throughput

0.515

High

1030373

JPH3
Junctophilin-3

1

1

High-throughput

0.515

High

951935

SYCY2
Syncytin-2

1

0

High-throughput

0.493

High

1030360

SGCB
Beta-sarcoglycan

1

0

High-throughput

0.493

High

1030358

NTCP
Hepatic sodium/bile acid cotransporter

1

1

High-throughput

0.481

High

385659

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.460

High

1030356

BIK
Bcl-2-interacting killer

1

0

High-throughput

0.460

High

184160

RER1
Protein RER1

1

0

Small-scale

0.458

High

1030357

AQP6
Aquaporin-6

1

3

High-throughput

0.439

High

1030366

TMM31
Transmembrane protein 31

1

1

High-throughput

0.439

High

1030387

SAR1A
Small COPII coat GTPase SAR1A

1

1

High-throughput

0.439

High

1030369

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

1

Small-scale

0.437

High

1030391

AMFR
E3 ubiquitin-protein ligase AMFR

1

1

Small-scale

0.437

High

181308

PGRC2
Membrane-associated progesterone receptor component 2

2

0

High-throughput

0.316

High

926760

VMAT1
Chromaffin granule amine transporter

2

0

High-throughput

0.316

High

1030363

SHSL1
Protein shisa-like-1

2

0

High-throughput

0.316

High

1030367

CP054
Transmembrane protein C16orf54

2

0

High-throughput

0.316

High

1030370

TM139
Transmembrane protein 139

2

0

High-throughput

0.316

High

1030384

TMX1
Thioredoxin-related transmembrane protein 1

2

0

High-throughput

0.316

High

1030385

REEP4
Receptor expression-enhancing protein 4

2

0

High-throughput

0.316

High

1030388

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

1030393

DDX52
Probable ATP-dependent RNA helicase DDX52

1

0

High-throughput

0.282

High

1030378

TMM80
Transmembrane protein 80

1

0

High-throughput

0.268

Low

1030372

GPX8
Probable glutathione peroxidase 8

1

0

High-throughput

0.251

Low

698590

CALX
Calnexin

1

0

Small-scale

0.249

Low

828354

PEX19
Peroxisomal biogenesis factor 19

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025