HitPredict

Interactor 1: SDSL (Q96GA7)
Serine dehydratase-like (Cancerous serine dehydratase) (cSDH) (Glutamate racemase) (EC 5.1.1.3) (L-serine deaminase) (EC 4.3.1.17) (L-serine dehydratase/L-threonine deaminase) (SDHL) (L-threonine dehydratase) (TDH) (EC 4.3.1.19) (Serine dehydratase 2) (SDH 2)
Gene: SDSL

Interactor 2: SDSL (Q96GA7)
Serine dehydratase-like (Cancerous serine dehydratase) (cSDH) (Glutamate racemase) (EC 5.1.1.3) (L-serine deaminase) (EC 4.3.1.17) (L-serine dehydratase/L-threonine deaminase) (SDHL) (L-threonine dehydratase) (TDH) (EC 4.3.1.19) (Serine dehydratase 2) (SDH 2)
Gene: SDSL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.946

The method score is based on:

Property Details
Experiments 25416956, 16189514, 21516116, 32296183, 31515488, unassigned1304
Identification Methods two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PALP~PALP
Common GO terms GO:0003941 - L-serine ammonia-lyase activity
GO:0004794 - threonine deaminase activity
GO:0005829 - cytosol
GO:0006565 - L-serine catabolic process
GO:0006629 - lipid metabolic process
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 329
Hs

1 329
+ Hs
+ At
+ Hs
+ Zm
+ Sl
+ Zm
+ Sc
+ At
+ Ec
+ Sc
+ Cj
+ Dm
+ Ce
+ Sc
+ Sp
+ Sc
+ At
+ Ec
+ Sc
+ Cj

Service provided by Combinatics, Japan

Last updated: 11Aug2025