HitPredict - High confidence protein-protein interactions

Interactor 1: GMPPA (Q96IJ6)
Mannose-1-phosphate guanylyltransferase regulatory subunit alpha (GDP-mannose pyrophosphorylase A) (GMPP-alpha) (GTP-mannose-1-phosphate guanylyltransferase alpha)
Gene: GMPPA

Interactor 2: GMPPA (Q96IJ6)
Mannose-1-phosphate guanylyltransferase regulatory subunit alpha (GDP-mannose pyrophosphorylase A) (GMPP-alpha) (GTP-mannose-1-phosphate guanylyltransferase alpha)
Gene: GMPPA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	NTP_transferase~NTP_transferase
Common GO terms	GO:0004857 - enzyme inhibitor activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006486 - protein glycosylation GO:0009298 - GDP-mannose biosynthetic process and 17 others more... GO:0009890 - negative regulation of biosynthetic process GO:0016740 - transferase activity GO:0019673 - GDP-mannose metabolic process GO:0019899 - enzyme binding GO:0021537 - telencephalon development GO:0045934 - negative regulation of nucleobase-containing compound metabolic process GO:0045936 - negative regulation of phosphate metabolic process GO:0048644 - muscle organ morphogenesis GO:0050890 - cognition GO:0050905 - neuromuscular process GO:0051402 - neuron apoptotic process GO:0060538 - skeletal muscle organ development GO:0061744 - motor behavior GO:0062014 - negative regulation of small molecule metabolic process GO:0070062 - extracellular exosome GO:0120508 - GDP-mannose pyrophosphorylase complex GO:0140299 - molecular sensor activity
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1	420
Hs

1	420

Service provided by Combinatics, Japan

Last updated: 11Aug2025