Protein: GMPPA
Mannose-1-phosphate guanylyltransferase regulatory subunit alpha (GDP-mannose pyrophosphorylase A) (GMPP-alpha) (GTP-mannose-1-phosphate guanylyltransferase alpha)

Gene: GMPPA
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q96IJ6

Gene Ontology (top 5):
GO:0004857 - enzyme inhibitor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006486 - protein glycosylation
GO:0009298 - GDP-mannose biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1394229

GMPPB
Mannose-1-phosphate guanylyltransferase catalytic subunit beta

8

13

High-throughput

0.973

High

1394214

GMPPA
Mannose-1-phosphate guanylyltransferase regulatory subunit alpha

1

12

High-throughput

0.698

High

1394219

GOLP3
Golgi phosphoprotein 3

4

2

High-throughput

0.691

High

1156181

ZYX
Zyxin

3

1

High-throughput

0.662

High

1394223

PAK5
Serine/threonine-protein kinase PAK 5

2

2

High-throughput

0.628

High

762414

BTC
Probetacellulin [Cleaved into: Betacellulin

2

2

High-throughput

0.590

High

242593

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.584

High

831247

CCNF
Cyclin-F

2

4

High-throughput

0.584

High

1391941

DCNL1
DCN1-like protein 1

2

0

High-throughput

0.580

High

1327781

SH2D3
SH2 domain-containing protein 3C

2

0

High-throughput

0.547

High

457619

TBB5
Tubulin beta chain

1

1

High-throughput

0.536

High

564213

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

1095925

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

16

High-throughput

0.536

High

1113997

CUL3
Cullin-3

1

2

High-throughput

0.536

High

1033410

CDR2
Cerebellar degeneration-related protein 2

1

0

High-throughput

0.518

High

856867

BAG6
Large proline-rich protein BAG6

1

1

High-throughput

0.515

High

1394227

PADI4
Protein-arginine deiminase type-4

1

0

High-throughput

0.513

High

728383

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

Small-scale

0.501

High

160002

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.493

High

167359

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

594079

NCK1
SH2/SH3 adapter protein NCK1

1

1

High-throughput

0.481

High

124638

EYA2
Protein phosphatase EYA2

1

1

High-throughput

0.479

High

294178

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.479

High

537712

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

714353

PML
Protein PML

1

2

High-throughput

0.479

High

766767

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

1178307

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

1221016

FBW10
F-box/WD repeat-containing protein 10

1

4

High-throughput

0.479

High

1255077

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

1334778

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1380626

FBX32
F-box only protein 32

1

1

High-throughput

0.479

High

1394215

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.479

High

1394220

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

1394221

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

1394222

BRD7
Bromodomain-containing protein 7

1

4

High-throughput

0.479

High

1394224

HECW2
E3 ubiquitin-protein ligase HECW2

1

3

High-throughput

0.479

High

1394225

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1394226

FBXL7
F-box/LRR-repeat protein 7

1

1

Small-scale

0.479

High

1394228

FND3A
Fibronectin type-III domain-containing protein 3A

1

1

High-throughput

0.479

High

377687

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

697991

CALR
Calreticulin

1

0

High-throughput

0.458

High

1335507

MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14

1

0

High-throughput

0.458

High

259049

DNJA2
DnaJ homolog subfamily A member 2

1

3

High-throughput

0.445

High

328111

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

2

High-throughput

0.445

High

407689

S100B
Protein S100-B

1

1

High-throughput

0.445

High

1209518

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

1394217

NMNA2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2

1

1

High-throughput

0.445

High

344566

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

1

High-throughput

0.439

High

505754

ZN688
Zinc finger protein 688

1

1

High-throughput

0.439

High

1100237

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.437

High

162116

ACOT8
Acyl-coenzyme A thioesterase 8

1

0

High-throughput

0.426

High

277465

AVIL
Advillin

1

0

High-throughput

0.426

High

350305

DDAH2
Putative hydrolase DDAH2

1

0

High-throughput

0.426

High

626332

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

0

High-throughput

0.426

High

3273

A0A0S2Z4D7
NCK adaptor protein 1 isoform 2

1

1

High-throughput

0.417

High

3631

A0A0S2Z6P0
Zinc finger protein 688 isoform 2

1

1

High-throughput

0.417

High

73843

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

1

High-throughput

0.407

High

1104059

RM49
Large ribosomal subunit protein mL49

1

1

High-throughput

0.407

High

1394216

TCPQM
T-complex protein 1 subunit theta-like 2

1

2

High-throughput

0.407

High

1370617

GPKOW
G-patch domain and KOW motifs-containing protein

2

0

High-throughput

0.316

High

388549

CRP

1

0

High-throughput

0.299

High

1031940

NC2B
Protein Dr1

1

0

High-throughput

0.268

Low

1096166

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.268

Low

1394230

TF3C3
General transcription factor 3C polypeptide 3

1

0

High-throughput

0.268

Low

1226499

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

1394218

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025