Interactor 1: GMPPA (Q96IJ6)
Mannose-1-phosphate guanylyltransferase regulatory subunit alpha (GDP-mannose pyrophosphorylase A) (GMPP-alpha) (GTP-mannose-1-phosphate guanylyltransferase alpha)
Gene: GMPPA

Interactor 2: GMPPB (Q9Y5P6)
Mannose-1-phosphate guanylyltransferase catalytic subunit beta (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B) (GTP-mannose-1-phosphate guanylyltransferase beta)
Gene: GMPPB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 25416956, 26186194, 16189514, 28514442, 33961781, 32296183, unassigned1304, 31515488
Identification Methods two hybrid, affinity chromatography technology, validated two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains NTP_transferase~NTP_transferase
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006486 - protein glycosylation
GO:0009298 - GDP-mannose biosynthetic process
GO:0019673 - GDP-mannose metabolic process
and 1 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 420
Hs

1 360
+ Hs
+ Dm
+ At
+ At
+ At
+ Sp
+ Sp
+ At
+ At
+ Hs
+ Sp
+ Hs
+ At

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Last updated: 11Aug2025