HitPredict

Interactor 1: SQSTM (O08623)
Sequestosome-1 (Protein kinase C-zeta-interacting protein) (PKC-zeta-interacting protein) (Ubiquitin-binding protein p62)
Gene: Sqstm1

Interactor 2: KPCG (P63319)
Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)
Gene: Prkcg

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	26199377
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PB1~Pkinase
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008270 - zinc ion binding GO:0031397 - negative regulation of protein ubiquitination
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 439 Rn			1 697
+	Rn
		139620 SQSTM_RAT (1-439): 0: 782: 100.00		KPCB_RAT (1-681): 0: 737: 67.94
+	Hs
		616709 SQSTM_HUMAN (1-439): 0: 713: 88.46		KS6B1_HUMAN (333-695): 2.97e-149: 445: 37.67
+	Rn
		139610 SQSTM_RAT (1-439): 0: 782: 100.00		KPCD_RAT (6-185): 3.2e-62: 221: 36.51
+	Mm
		661009 SQSTM_MOUSE (1-439): 0: 772: 96.83		KPCD_MOUSE (6-193): 9.27e-63: 223: 35.53
+	Rn
		139611 SQSTM_RAT (1-439): 0: 782: 100.00		KPCE_RAT (20-209): 5.26e-56: 205: 41.92
+	Rn
		139624 SQSTM_RAT (1-439): 0: 782: 100.00		KPCL_RAT (30-195): 1.71e-51: 192: 40.57
+	Hs
		984491 SQSTM_HUMAN (1-439): 0: 713: 88.46		KPCD_HUMAN (6-166): 3.3e-63: 224: 40.24
+	Rn
		94344 SQSTM_RAT (1-439): 0: 782: 100.00		KPCI_RAT (21-85): 3.3e-12: 71.6: 43.08
+	Rn
		139612 SQSTM_RAT (1-439): 0: 782: 100.00		KPCZ_RAT (21-85): 2.83e-10: 65.5: 36.92
+	Mm
		973811 SQSTM_MOUSE (1-439): 0: 772: 96.83		KPCZ_MOUSE (21-85): 3.17e-10: 65.5: 36.92
+	Hs
		784001 SQSTM_HUMAN (1-439): 0: 713: 88.46		KPCI_HUMAN (21-85): 2.42e-12: 72: 43.08
+	Hs
		983828 SQSTM_HUMAN (1-439): 0: 713: 88.46		KPCZ_HUMAN (21-85): 2.58e-10: 65.5: 36.92
+	Dm
		54642 REF2P_DROME (110-167): 1.12e-17: 87.5: 41.67		APKC_DROME (8-85): 6.35e-13: 73.9: 38.46