Interactor 1: SH2B3 (O09039)
SH2B adapter protein 3 (Lymphocyte adapter protein) (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk)
Gene: SH2B3
Interactor 2: JAK2 (Q62120)
Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)
Gene: JAK2
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30755420 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FERM_F1~SH2, PK_Tyr_Ser-Thr~SH2, SH2~SH2 |
| Common GO terms | GO:0005886 - plasma membrane GO:0008285 - negative regulation of cell population proliferation GO:0035556 - intracellular signal transduction GO:0036016 - cellular response to interleukin-3 |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
