HitPredict

Interactor 1: VRK1 (Q99986)
Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1)
Gene: VRK1

Interactor 2: VRK1 (Q99986)
Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1)
Gene: VRK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.956

The method score is based on:

Property Details
Experiments 26068304, 28927264, 10951572, 11883897, 29340707, 21920476, 22621922
Identification Methods enzymatic study, affinity chromatography technology, protein kinase assay, phosphotransferase assay
Interaction Type direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000785 - chromatin
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 26 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 396
Hs

1 396
+ At
+ At
+ Mm
+ At
+ At
+ At
+ Hs
+ At
+ At
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ At
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025