Protein: FCF2
rRNA-processing protein FCF2 (FAF1 copurifying factor 2)

Gene: FCF2
Organism: Saccharomyces cerevisiae S288C
Interactions: 102
UniProt ID: Q12035

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

748740

ENP1
Essential nuclear protein 1

3

0

High-throughput

0.613

High

979072

DHR1
Probable ATP-dependent RNA helicase DHR1

3

0

High-throughput

0.613

High

775404

FAF1
Protein FAF1

2

0

Small-scale

0.585

High

635665

PWP2
Periodic tryptophan protein 2

2

2

Small-scale

0.584

High

985831

UTP21
U3 small nucleolar RNA-associated protein 21

2

2

Small-scale

0.584

High

1014909

NOP58
Nucleolar protein 58

2

2

High-throughput

0.584

High

634814

KRR1
KRR1 small subunit processome component

2

0

High-throughput

0.559

High

792623

UTP10
U3 small nucleolar RNA-associated protein 10

2

0

High-throughput

0.559

High

865433

CSL4
Exosome complex component CSL4

2

0

High-throughput

0.559

High

979744

UTP14
U3 small nucleolar RNA-associated protein 14

2

0

High-throughput

0.559

High

987685

NOC4
Nucleolar complex protein 4

2

0

High-throughput

0.559

High

471306

RS22A
Small ribosomal subunit protein uS8A

2

1

High-throughput

0.533

High

698610

MRE11
Double-strand break repair protein MRE11

1

0

High-throughput

0.493

High

141568

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

407383

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

480370

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

700111

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

2

High-throughput

0.479

High

700671

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

707156

DCA13
Protein SOF1

1

1

High-throughput

0.479

High

743047

GBLP
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.479

High

755010

RRP4
Exosome complex component RRP4

1

1

High-throughput

0.479

High

767439

UTP7
U3 small nucleolar RNA-associated protein 7

1

1

High-throughput

0.479

High

809601

RRP41
Exosome complex component SKI6

1

2

High-throughput

0.479

High

860824

RRP46
Exosome complex component RRP46

1

2

High-throughput

0.479

High

864746

ESF2
Pre-rRNA-processing protein ESF2

1

1

High-throughput

0.479

High

866285

NOP15
Ribosome biogenesis protein 15

1

1

High-throughput

0.479

High

973693

UTP17
NET1-associated nuclear protein 1

1

3

High-throughput

0.479

High

975858

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.479

High

978648

UTP5
U3 small nucleolar RNA-associated protein 5

1

2

High-throughput

0.479

High

979260

UTP15
U3 small nucleolar RNA-associated protein 15

1

1

High-throughput

0.479

High

984322

RRP45
Exosome complex component RRP45

1

2

High-throughput

0.479

High

985437

UTP13
U3 small nucleolar RNA-associated protein 13

1

2

High-throughput

0.479

High

987616

RRP9
Ribosomal RNA-processing protein 9

1

1

High-throughput

0.479

High

988653

UTP4
U3 small nucleolar RNA-associated protein 4

1

2

High-throughput

0.479

High

993682

RRP44
Exosome complex exonuclease DIS3

1

1

High-throughput

0.479

High

1014903

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.479

High

1014905

UTP12
U3 small nucleolar RNA-associated protein 12

1

2

High-throughput

0.479

High

1014906

RRP42
Exosome complex component RRP42

1

2

High-throughput

0.479

High

1014907

NOP56
Nucleolar protein 56

1

2

High-throughput

0.479

High

408173

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

413757

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

426196

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

482503

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

593720

DBP4
ATP-dependent RNA helicase HCA4

1

0

High-throughput

0.458

High

630286

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

630557

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

632140

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

645702

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

663594

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

711088

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

716004

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.458

High

730164

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

733615

RL1D1
Ribosome biogenesis protein UTP30

1

0

High-throughput

0.458

High

755214

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

756808

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.458

High

758486

RRP8
25S rRNA

1

0

High-throughput

0.458

High

768129

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.458

High

772697

UTP18
U3 small nucleolar RNA-associated protein 18

1

0

High-throughput

0.458

High

774293

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

774762

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.458

High

784536

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.458

High

799875

ROK1
ATP-dependent RNA helicase ROK1

1

0

High-throughput

0.458

High

810947

MTR4
ATP-dependent RNA helicase DOB1

1

0

High-throughput

0.458

High

811370

NOP9
Nucleolar protein 9

1

0

Small-scale

0.458

High

811575

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

High-throughput

0.458

High

816923

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.458

High

816987

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.458

High

860766

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.458

High

861047

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.458

High

866079

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.458

High

866634

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

High-throughput

0.458

High

967815

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

970485

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.458

High

982911

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.458

High

983781

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

986765

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

987104

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.458

High

988484

BFR2
Protein BFR2

1

0

High-throughput

0.458

High

993371

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.458

High

994584

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.458

High

995825

SGO1
Shugoshin

1

0

High-throughput

0.458

High

995871

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

996342

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

997058

BMS1
Ribosome biogenesis protein BMS1

1

0

High-throughput

0.458

High

1014902

SAS10
Something about silencing protein 10

1

0

High-throughput

0.458

High

1014904

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

1014908

RRP36
rRNA biogenesis protein RRP36

1

0

High-throughput

0.458

High

1014910

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

1014912

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.458

High

1014913

PNO1
Pre-rRNA-processing protein PNO1

1

0

High-throughput

0.458

High

733970

RPF2
Ribosome biogenesis protein RPF2

1

1

High-throughput

0.445

High

1014911

RS22B
Small ribosomal subunit protein uS8B

1

1

High-throughput

0.437

High

784364

COPB
Coatomer subunit beta

1

0

High-throughput

0.269

Low

358302

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

480938

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

706545

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

737236

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.249

Low

752719

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

820225

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

991337

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

496104

RLA3
Large ribosomal subunit protein P1B

1

0

High-throughput

0.238

Low

969274

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024