HitPredict

Interactor 1: PRP46 (O13615)
Pre-mRNA-splicing factor prp5 (Complexed with cdc5 protein 1) (Pre-mRNA-processing protein 5)
Gene: prp5

Interactor 2: SYF1 (Q9P7R9)
Pre-mRNA-splicing factor cwf3 (Complexed with cdc5 protein 3)
Gene: cwf3

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	10409726
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0000974 - Prp19 complex GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0071014 - post-mRNA release spliceosomal complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 473 Sp			1 790
+	Hs
		1288323 SNR40_HUMAN (281-472): 3.97e-45: 162: 20.41		SYF1_HUMAN (25-790): 3.71e-156: 477: 42.05
+	Hs
		209486 PLRG1_HUMAN (1-232): 2.22e-37: 145: 11.84		SYF1_HUMAN (25-790): 3.71e-156: 477: 42.05
+	Dm
		54179 Q9VYQ9_DROME (1-232): 6.88e-40: 151: 13.06		SYF1_DROME (11-778): 1.47e-152: 469: 41.92
+	Sc
		978489 PRP46_YEAST (111-398): 2.9e-59: 203: 22.26		SYF1_YEAST (7-751): 2.18e-86: 293: 22.77
+	Sp
		141996 PRP46_SCHPO (1-473): 9.41e-116: 350: 100.00		CLF1_SCHPO (162-775): 1.96e-33: 139: 13.74
+	Hs
		300222 FBXW7_HUMAN (3-312): 8e-65: 223: 16.51		PRP6_HUMAN (212-785): 1.1e-40: 163: 12.88
+	Hs
		1199241 FBXW7_HUMAN (3-312): 8e-65: 223: 16.51		PRP39_HUMAN (4-456): 3.31e-38: 154: 14.15
+	Hs
		300095 WDR5_HUMAN (281-472): 2.99e-55: 189: 21.03		PRP6_HUMAN (212-785): 1.1e-40: 163: 12.88
+	Hs
		175317 FBW1A_HUMAN (103-399): 2.36e-67: 228: 25.48		OGT1_HUMAN (486-789): 6.1e-27: 120: 10.00
+	Hs
		175177 TBL1R_HUMAN (184-472): 1.27e-62: 213: 16.93		OGT1_HUMAN (486-789): 6.1e-27: 120: 10.00
+	Sc
		1015445 PRP46_YEAST (111-398): 2.9e-59: 203: 22.26		CLF1_YEAST (8-658): 1.02e-29: 127: 14.41
+	Hs
		300229 SNR40_HUMAN (281-472): 3.97e-45: 162: 20.41		PRP6_HUMAN (212-785): 1.1e-40: 163: 12.88
+	Hs
		174768 WDR5_HUMAN (281-472): 2.99e-55: 189: 21.03		OGT1_HUMAN (486-789): 6.1e-27: 120: 10.00
+	Hs
		1288293 SNR40_HUMAN (281-472): 3.97e-45: 162: 20.41		CRNL1_HUMAN (258-786): 4.64e-34: 142: 15.06
+	Hs
		903230 WDR5_HUMAN (281-472): 2.99e-55: 189: 21.03		RRP5_HUMAN (1-256): 4.73e-23: 107: 16.61
+	Hs
		209476 PLRG1_HUMAN (1-232): 2.22e-37: 145: 11.84		CRNL1_HUMAN (258-786): 4.64e-34: 142: 15.06
+	Hs
		903236 WDR5_HUMAN (281-472): 2.99e-55: 189: 21.03		SART3_HUMAN (17-481): 4.37e-17: 88.1: 10.98
+	Hs
		1058000 SNR40_HUMAN (281-472): 3.97e-45: 162: 20.41		RRP5_HUMAN (1-256): 4.73e-23: 107: 16.61
+	Hs
		1022304 SNR40_HUMAN (281-472): 3.97e-45: 162: 20.41		CSTF3_HUMAN (6-240): 5.6e-10: 65: 15.95
+	Hs
		1058048 NLE1_HUMAN (13-151): 1.99e-22: 101: 9.66		RRP5_HUMAN (1-256): 4.73e-23: 107: 16.61