HitPredict

Interactor 1: SWR1 (O13682)
Helicase swr1 (EC 3.6.4.12)
Gene: SWR1

Interactor 2: H2AZ (P48003)
Histone H2A.Z
Gene: pht1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	19910462, 19693008
Identification Methods	affinity chromatography technology, biochemical
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1288 Sp			1 139
+	Hs
		1087132 INO80_HUMAN (58-1262): 0: 703: 26.14		H2A2C_HUMAN (1-137): 1.49e-54: 169: 57.25
+	Hs
		391964 INO80_HUMAN (58-1262): 0: 703: 26.14		H2A1B_HUMAN (1-136): 8.32e-54: 167: 57.66
+	Sc
		983753 SWR1_YEAST (30-1240): 0: 719: 41.67		H2AZ_YEAST (7-131): 6.84e-45: 144: 68.75
+	Hs
		391915 CHD8_HUMAN (776-1287): 5.52e-87: 315: 22.12		H2A1B_HUMAN (1-136): 8.32e-54: 167: 57.66
+	Hs
		470170 CHD8_HUMAN (776-1287): 5.52e-87: 315: 22.12		H2AZ_HUMAN (1-132): 8.25e-54: 167: 65.15
+	Hs
		1018640 CHD3_HUMAN (815-1287): 1.54e-84: 306: 21.74		H2A1H_HUMAN (1-136): 2.56e-54: 168: 56.93
+	Hs
		391675 CHD3_HUMAN (815-1287): 1.54e-84: 306: 21.74		H2A1B_HUMAN (1-136): 8.32e-54: 167: 57.66
+	Hs
		391728 CHD9_HUMAN (804-1287): 6.37e-81: 296: 23.47		H2A1B_HUMAN (1-136): 8.32e-54: 167: 57.66
+	Mm
		470232 SMCA4_MOUSE (772-1285): 8.2e-81: 295: 20.25		H2AZ_MOUSE (1-132): 8.25e-54: 167: 65.15
+	Hs
		391846 EP400_HUMAN (847-1287): 1.78e-79: 291: 30.57		H2A1B_HUMAN (1-136): 8.32e-54: 167: 57.66
+	Hs
		470128 EP400_HUMAN (847-1287): 1.78e-79: 291: 30.57		H2AZ_HUMAN (1-132): 8.25e-54: 167: 65.15
+	Hs
		469971 SMCA4_HUMAN (772-1285): 9.98e-79: 288: 19.11		H2AZ_HUMAN (1-132): 8.25e-54: 167: 65.15
+	Hs
		151474 CHD2_HUMAN (801-1200): 6.48e-77: 282: 26.33		H2A1B_HUMAN (1-136): 8.32e-54: 167: 57.66
+	Hs
		229433 SMCA5_HUMAN (980-1280): 8.32e-71: 260: 33.66		H2A2B_HUMAN (1-134): 2.39e-55: 171: 57.78
+	Hs
		229279 SMCA5_HUMAN (980-1280): 8.32e-71: 260: 33.66		H2A1B_HUMAN (1-136): 8.32e-54: 167: 57.66
+	Hs
		229286 SMCA5_HUMAN (980-1280): 8.32e-71: 260: 33.66		H2AZ_HUMAN (1-132): 8.25e-54: 167: 65.15
+	Hs
		469951 SMCA1_HUMAN (980-1280): 3.82e-67: 249: 31.75		H2AZ_HUMAN (1-132): 8.25e-54: 167: 65.15
+	Hs
		470278 SMCA1_HUMAN (980-1280): 3.82e-67: 249: 31.75		H2A1_HUMAN (1-136): 7.88e-54: 167: 56.93
+	Hs
		470059 SRCAP_HUMAN (67-420): 2.98e-53: 208: 15.36		H2AZ_HUMAN (1-132): 8.25e-54: 167: 65.15
+	Sc
		744936 ISW1_YEAST (1005-1254): 1.41e-55: 213: 32.32		H2AZ_YEAST (7-131): 6.84e-45: 144: 68.75