HitPredict

Interactor 1: D6PK (Q9FG74)
Serine/threonine-protein kinase D6PK (EC 2.7.11.1) (D6 protein kinase) (Serine/threonine-protein kinase 64) (AtPK64) (Serine/threonine-protein kinase AGC1-1)
Gene: D6PK

Interactor 2: PDPK1 (Q9XF67)
3-phosphoinositide-dependent protein kinase 1 (AtPDK1) (EC 2.7.11.1)
Gene: PDPK1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	16973627
Identification Methods	pull down, in-gel kinase assay
Interaction Type	physical association, enzymatic reaction

Property	Details
Interacting Pfam domains	Pkinase~Pkinase
Common GO terms	GO:0004672 - protein kinase activity GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0016301 - kinase activity GO:0070300 - phosphatidic acid binding and 1 others more... GO:0106310 - protein serine kinase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 498 At			1 491
+	At
		1457148 D6KL1_ARATH (4-498): 6.68e-147: 432: 79.28		PDPK1_ARATH (1-491): 0: 524: 100.00
+	At
		1184531 D6KL2_ARATH (2-498): 2.1e-141: 420: 70.04		PDPK1_ARATH (1-491): 0: 524: 100.00
+	At
		1169326 AGC17_ARATH (15-498): 1.92e-134: 401: 52.94		PDPK1_ARATH (1-491): 0: 524: 100.00
+	At
		1443196 Q9LUK3_ARATH (2-498): 1.47e-134: 400: 55.03		PDPK1_ARATH (1-491): 0: 524: 100.00
+	At
		1342287 Q8RY37_ARATH (3-498): 3.65e-130: 397: 54.56		PDPK1_ARATH (1-491): 0: 524: 100.00
+	At
		1443082 AGC15_ARATH (10-498): 1.87e-131: 395: 53.85		PDPK1_ARATH (1-491): 0: 524: 100.00
+	At
		100307 RHS3_ARATH (6-498): 3.51e-132: 393: 50.59		PDPK1_ARATH (1-491): 0: 524: 100.00
+	At
		1456704 KIPK2_ARATH (5-495): 3.95e-126: 391: 48.71		PDPK1_ARATH (1-491): 0: 524: 100.00
+	At
		1441226 KIPK1_ARATH (5-464): 1.24e-123: 385: 54.14		PDPK1_ARATH (1-491): 0: 524: 100.00
+	At
		1053194 D6KL3_ARATH (82-465): 2.01e-124: 376: 70.33		PDPK1_ARATH (1-491): 0: 524: 100.00
+	At
		1444235 Q9M1P3_ARATH (109-456): 7.51e-124: 371: 52.97		PDPK1_ARATH (1-491): 0: 524: 100.00
+	At
		1225852 PID2_ARATH (28-498): 6.87e-118: 358: 43.02		PDPK1_ARATH (1-491): 0: 524: 100.00
+	Sl
		1205386 Q5I6E9_SOLLC (3-458): 8.96e-128: 389: 61.12		Q5I6E8_SOLLC (2-491): 3.44e-171: 492: 80.61
+	At
		264952 PID_ARATH (37-498): 5.07e-115: 348: 44.59		PDPK1_ARATH (1-491): 0: 524: 100.00
+	At
		1443202 WAG2_ARATH (84-461): 6.97e-105: 323: 44.44		PDPK1_ARATH (1-491): 0: 524: 100.00
+	Hs
		728184 KPCT_HUMAN (26-422): 3.77e-118: 364: 21.05		AKT1_HUMAN (2-371): 1.9e-146: 429: 31.18
+	Hs
		728441 LATS2_HUMAN (92-497): 3.6e-114: 363: 26.53		AKT1_HUMAN (2-371): 1.9e-146: 429: 31.18
+	Hs
		193554 KPCT_HUMAN (26-422): 3.77e-118: 364: 21.05		PDPK1_HUMAN (18-491): 5.02e-142: 420: 35.59
+	Hs
		728491 AKT3_HUMAN (39-497): 2.56e-117: 355: 17.62		AKT1_HUMAN (2-371): 1.9e-146: 429: 31.18
+	Hs
		728630 AKT3_HUMAN (39-497): 2.56e-117: 355: 17.62		AKT2_HUMAN (2-359): 7.17e-146: 428: 30.64