HitPredict

Interactor 1: AFAD (O35889)
Afadin (Afadin adherens junction formation factor) (Protein Af-6)
Gene: Afdn

Interactor 2: NRX2A (Q63374)
Neurexin-2 (Neurexin II-alpha) (Neurexin-2-alpha)
Gene: Nrxn2

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	9707552
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction GO:0050839 - cell adhesion molecule binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1829 Rn			1 1715
+	Rn
		677793 DLG4_RAT (971-1245): 9.12e-30: 130: 17.10		NRX2A_RAT (1-1715): 0: 1391: 100.00
+	Hs
		876366 AFAD_HUMAN (1-1829): 0: 1121: 92.63		NOTC2_HUMAN (119-1169): 7.31e-61: 234: 10.55
+	Rn
		193553 AFAD_RAT (1-1829): 0: 1129: 100.00		NRX1B_RAT (1615-1715): 6.26e-45: 172: 83.33
+	Hs
		876339 AFAD_HUMAN (1-1829): 0: 1121: 92.63		NRX1B_HUMAN (1615-1715): 4.59e-43: 166: 83.33
+	Rn
		193552 AFAD_RAT (1-1829): 0: 1129: 100.00		NRX3A_RAT (5-143): 8.11e-22: 105: 17.24
+	Hs
		876548 AFAD_HUMAN (1-1829): 0: 1121: 92.63		NRX3A_HUMAN (5-152): 1.76e-22: 107: 16.88
+	Hs
		876340 AFAD_HUMAN (1-1829): 0: 1121: 92.63		NRX2B_HUMAN (498-665): 3.66e-13: 76.6: 15.96
+	Dm
		422801 Q8IPP3_DROME (1-1679): 0: 713: 32.24		NOTCH_DROME (119-1002): 4.09e-49: 195: 8.81
+	Dm
		1214093 Q8IPP3_DROME (1-1679): 0: 713: 32.24		Q8IQH0_DROME (31-187): 8.39e-15: 82.4: 19.11
+	Dm
		1214094 Q8IPP3_DROME (1-1679): 0: 713: 32.24		NRX4_DROME (31-187): 8.46e-15: 82.4: 19.11
+	Dm
		1214752 Q95TT5_DROME (1-1275): 0: 682: 39.06		Q8IQH0_DROME (31-187): 8.39e-15: 82.4: 19.11
+	Dm
		422756 Q24279_DROME (1-1546): 1.59e-144: 495: 22.26		NOTCH_DROME (119-1002): 4.09e-49: 195: 8.81
+	Hs
		129762 KIF14_HUMAN (41-700): 5.53e-81: 298: 14.33		AGRIN_HUMAN (1103-1427): 3.24e-40: 166: 16.87
+	Hs
		1066649 KIF14_HUMAN (41-700): 5.53e-81: 298: 14.33		CNTP4_HUMAN (7-186): 3.27e-13: 77.4: 19.36
+	Dm
		113050 M9NFI9_DROME (1006-1151): 7.04e-23: 109: 29.81		CADN_DROME (11-289): 7.61e-32: 138: 12.96
+	Mm
		1143490 DLG4_MOUSE (971-1245): 7.79e-30: 130: 17.10		NRX1A_MOUSE (5-143): 1.16e-21: 105: 17.36
+	Dm
		1214753 PATJ_DROME (994-1171): 1.54e-31: 136: 29.12		Q8IQH0_DROME (31-187): 8.39e-15: 82.4: 19.11
+	Dm
		1277000 PATJ_DROME (994-1171): 1.54e-31: 136: 29.12		NRX4_DROME (31-187): 8.46e-15: 82.4: 19.11
+	Mm
		222920 DLG4_MOUSE (971-1245): 7.79e-30: 130: 17.10		CNTP1_MOUSE (7-186): 3.5e-14: 80.4: 22.04
+	Dm
		112905 M9NEY3_DROME (1006-1151): 6.57e-23: 109: 29.81		NRX1_DROME (3-189): 3.36e-14: 80.8: 20.81