HitPredict

Interactor 1: COMD5 (Q9GZQ3)
COMM domain-containing protein 5 (Hypertension-related calcium-regulated gene protein) (HCaRG)
Gene: COMMD5

Interactor 2: COMDA (Q9Y6G5)
COMM domain-containing protein 10
Gene: COMMD10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	1.00	0.942

Property	Details
Experiments	28514442, 32296183, 33961781, unassigned1304, 37172566, 23563313
Identification Methods	affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	COMM_domain~COMM_domain, COMM_HN~COMM_domain
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 224 Hs			1 202
+	Hs
		1428330 COMD5_HUMAN (1-224): 5.59e-143: 399: 100.00		COMD3_HUMAN (9-202): 2.19e-61: 191: 21.32
+	Hs
		1291793 COMD5_HUMAN (1-224): 5.59e-143: 399: 100.00		COMD7_HUMAN (10-200): 3.31e-59: 186: 14.14
+	Hs
		1428325 COMD5_HUMAN (1-224): 5.59e-143: 399: 100.00		COMD4_HUMAN (9-201): 6.38e-43: 144: 20.73
+	Hs
		1293503 COMD5_HUMAN (1-224): 5.59e-143: 399: 100.00		COMD2_HUMAN (7-198): 2.38e-09: 56.4: 11.98