Protein: COMD2
COMM domain-containing protein 2

Gene: COMD2, COMMD2
Organism: Homo sapiens
Interactions: 86
UniProt ID: Q86X83

Gene Ontology (top 5):
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1293520

COMDA
COMM domain-containing protein 10

6

7

High-throughput

0.945

High

1293486

COMD1
COMM domain-containing protein 1

6

0

Small-scale

0.896

High

1293504

COMD4
COMM domain-containing protein 4

6

0

High-throughput

0.895

High

1293511

COMD3
COMM domain-containing protein 3

8

1

High-throughput

0.865

High

257138

CCD22
Coiled-coil domain-containing protein 22

7

2

Small-scale

0.864

High

1278346

COMD6
COMM domain-containing protein 6

4

0

High-throughput

0.853

High

1201132

CCD93
Coiled-coil domain-containing protein 93

6

0

Small-scale

0.794

High

1291787

COMD7
COMM domain-containing protein 7

5

0

High-throughput

0.772

High

1293509

COMD8
COMM domain-containing protein 8

5

0

High-throughput

0.772

High

1293510

COMD9
COMM domain-containing protein 9

5

0

High-throughput

0.772

High

1293503

COMD5
COMM domain-containing protein 5

4

0

High-throughput

0.753

High

1181007

TR16L
Tripartite motif-containing protein 16-like protein

2

0

High-throughput

0.602

High

1293485

KIF2B
Kinesin-like protein KIF2B

2

0

High-throughput

0.602

High

789161

NUP62
Nuclear pore glycoprotein p62

2

0

High-throughput

0.576

High

626276

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

3

Small-scale

0.536

High

1026737

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

3

Small-scale

0.536

High

1030006

RELB
Transcription factor RelB

1

3

Small-scale

0.536

High

1045470

TF65
Transcription factor p65

1

3

Small-scale

0.536

High

1293482

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

1

High-throughput

0.536

High

1293521

R4GMX3
Polycomb complex protein BMI-1

1

2

High-throughput

0.514

High

123758

MYO1C
Unconventional myosin-Ic

1

0

High-throughput

0.513

High

297110

PAK3
Serine/threonine-protein kinase PAK 3

1

0

High-throughput

0.513

High

1022901

EFNB1
Ephrin-B1

1

0

High-throughput

0.513

High

1128421

ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

1

0

High-throughput

0.513

High

1243419

CNKR3
Connector enhancer of kinase suppressor of ras 3

1

0

High-throughput

0.513

High

1252022

TRI72
Tripartite motif-containing protein 72

1

0

High-throughput

0.513

High

1293491

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.513

High

1293492

STMN2
Stathmin-2

1

0

High-throughput

0.513

High

1293497

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.513

High

1293499

ODAD1
Outer dynein arm-docking complex subunit 1

1

1

High-throughput

0.489

High

422487

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1104210

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

1

High-throughput

0.479

High

1146938

PCBP2
Poly(rC)-binding protein 2

1

1

High-throughput

0.479

High

242182

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

934819

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

1143392

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.458

High

1293487

POC1A
POC1 centriolar protein homolog A

1

0

High-throughput

0.458

High

1293505

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1293513

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1293502

GNB1L
Guanine nucleotide-binding protein subunit beta-like protein 1

1

1

High-throughput

0.445

High

765677

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.437

High

292845

GRAP2
GRB2-related adapter protein 2

1

0

High-throughput

0.426

High

1209346

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1293493

NRBF2
Nuclear receptor-binding factor 2

1

0

High-throughput

0.426

High

1293507

DUS22
Dual specificity protein phosphatase 22

1

0

High-throughput

0.426

High

1293519

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

1

0

High-throughput

0.426

High

107286

F8VRH0

1

1

High-throughput

0.407

High

640212

EPHA1
Ephrin type-A receptor 1

1

1

High-throughput

0.407

High

1277141

VP35L
VPS35 endosomal protein-sorting factor-like

5

0

High-throughput

0.372

High

1293489

DEN10
DENN domain-containing protein 10

4

0

High-throughput

0.363

High

1293512

VPS29
Vacuolar protein sorting-associated protein 29

4

0

High-throughput

0.363

High

262258

SCN2B
Sodium channel regulatory subunit beta-2

4

0

High-throughput

0.360

High

63305

ODAD3
Outer dynein arm-docking complex subunit 3

3

0

High-throughput

0.347

High

171088

VP26C
Vacuolar protein sorting-associated protein 26C

3

0

High-throughput

0.345

High

1293490

FAT3
Protocadherin Fat 3

2

0

High-throughput

0.328

High

1293515

LAMP3
Lysosome-associated membrane glycoprotein 3

2

0

High-throughput

0.328

High

1293506

SACA1
Sperm acrosome membrane-associated protein 1

2

0

High-throughput

0.318

High

1293500

SCLT1
Sodium channel and clathrin linker 1

2

0

High-throughput

0.307

High

1293501

MIA2
Melanoma inhibitory activity protein 2

2

0

High-throughput

0.288

High

158843

AP3D1
AP-3 complex subunit delta-1

1

0

High-throughput

0.279

Low

175723

SR140
U2 snRNP-associated SURP motif-containing protein

1

0

High-throughput

0.279

Low

838755

MTREX
Exosome RNA helicase MTR4

1

0

High-throughput

0.279

Low

925945

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.279

Low

1065281

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.279

Low

1099422

SRSF6
Serine/arginine-rich splicing factor 6

1

0

High-throughput

0.279

Low

1179807

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1180456

C19L2
CWF19-like protein 2

1

0

High-throughput

0.279

Low

1233639

DRS7B
Dehydrogenase/reductase SDR family member 7B

1

0

High-throughput

0.279

Low

1293480

CNGA4
Cyclic nucleotide-gated channel alpha-4

1

0

High-throughput

0.279

Low

1293481

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.279

Low

1293483

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.279

Low

1293488

O13G1
Olfactory receptor 13G1

1

0

High-throughput

0.279

Low

1293494

CCD97
Coiled-coil domain-containing protein 97

1

0

High-throughput

0.279

Low

1293495

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.279

Low

1293496

SPF45
Splicing factor 45

1

0

High-throughput

0.279

Low

1293508

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.279

Low

1293514

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.279

Low

1293517

RBMX2
RNA-binding motif protein, X-linked 2

1

0

High-throughput

0.279

Low

1293518

SP16H
FACT complex subunit SPT16

1

0

High-throughput

0.279

Low

1279606

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.268

Low

290065

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.249

Low

1293484

VPS8
Vacuolar protein sorting-associated protein 8 homolog

1

0

High-throughput

0.249

Low

1293498

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

1

0

High-throughput

0.249

Low

1293516

NINL
Ninein-like protein

1

0

High-throughput

0.249

Low

518611

RAP2A
Ras-related protein Rap-2a

1

0

High-throughput

0.232

Low

777619

HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025