Protein: COMD3
COMM domain-containing protein 3 (Protein Bup) (Protein PIL)

Gene: COMD3, COMMD3
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q9UBI1

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0006814 - sodium ion transport
GO:1904813 - ficolin-1-rich granule lumen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1328853

COMD1
COMM domain-containing protein 1

7

1

Small-scale

0.965

High

1429668

COMD4
COMM domain-containing protein 4

6

1

High-throughput

0.943

High

1278368

COMD6
COMM domain-containing protein 6

4

1

High-throughput

0.892

High

1453655

COMD9
COMM domain-containing protein 9

5

0

High-throughput

0.877

High

257190

CCD22
Coiled-coil domain-containing protein 22

8

1

Small-scale

0.867

High

1293511

COMD2
COMM domain-containing protein 2

8

1

High-throughput

0.865

High

1428330

COMD5
COMM domain-containing protein 5

4

0

High-throughput

0.846

High

1458428

COMDA
COMM domain-containing protein 10

5

6

High-throughput

0.827

High

1201167

CCD93
Coiled-coil domain-containing protein 93

7

0

Small-scale

0.807

High

1451660

COMD8
COMM domain-containing protein 8

7

0

High-throughput

0.806

High

1291797

COMD7
COMM domain-containing protein 7

5

0

High-throughput

0.774

High

171113

VP26C
Vacuolar protein sorting-associated protein 26C

5

1

High-throughput

0.712

High

63325

ODAD3
Outer dynein arm-docking complex subunit 3

3

0

High-throughput

0.638

High

1128967

I13R2
Interleukin-13 receptor subunit alpha-2

3

0

High-throughput

0.634

High

1181014

TR16L
Tripartite motif-containing protein 16-like protein

3

1

High-throughput

0.604

High

1156955

CNGA3
Cyclic nucleotide-gated channel alpha-3

2

1

High-throughput

0.574

High

626388

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

1

Small-scale

0.536

High

1308519

CNGA4
Cyclic nucleotide-gated channel alpha-4

1

1

High-throughput

0.536

High

1458426

ZN337
Zinc finger protein 337

1

0

High-throughput

0.518

High

285732

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.513

High

844047

HD
Huntingtin

1

0

High-throughput

0.513

High

982570

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.513

High

1068326

AHNK
Neuroblast differentiation-associated protein AHNAK

1

0

High-throughput

0.513

High

1101073

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

1311045

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.513

High

1336948

ZN740
Zinc finger protein 740

1

0

High-throughput

0.513

High

1363348

DDX1
ATP-dependent RNA helicase DDX1

1

0

High-throughput

0.513

High

1365253

HS105
Heat shock protein 105 kDa

1

0

High-throughput

0.513

High

1458427

SKAP
Small kinetochore-associated protein

1

0

High-throughput

0.513

High

1397811

ODAD1
Outer dynein arm-docking complex subunit 1

1

1

High-throughput

0.489

High

1121356

TRI14
Tripartite motif-containing protein 14

1

1

High-throughput

0.479

High

373387

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

430457

JUN
Transcription factor Jun

1

0

High-throughput

0.458

High

1364646

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1458422

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1030043

RELB
Transcription factor RelB

1

1

Small-scale

0.445

High

983604

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

1

High-throughput

0.437

High

1255926

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

50941

SYCE3
Synaptonemal complex central element protein 3

1

0

High-throughput

0.426

High

1163256

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.426

High

1391825

AURKB
Aurora kinase B

1

0

High-throughput

0.426

High

71026

A8MTY9
VPS26 endosomal protein sorting factor C

1

1

High-throughput

0.407

High

72954

B1AKQ8
G protein subunit beta 1

1

1

High-throughput

0.407

High

1349637

DEN10
DENN domain-containing protein 10

6

0

High-throughput

0.378

High

1277154

VP35L
VPS35 endosomal protein-sorting factor-like

5

0

High-throughput

0.373

High

628381

CD33
Myeloid cell surface antigen CD33

4

0

High-throughput

0.360

High

1458421

VPS29
Vacuolar protein sorting-associated protein 29

4

0

High-throughput

0.358

High

1438448

SACA1
Sperm acrosome membrane-associated protein 1

3

0

High-throughput

0.347

High

1436007

PACC1
Proton-activated chloride channel

3

0

High-throughput

0.345

High

749415

TNFL8
Tumor necrosis factor ligand superfamily member 8

2

0

High-throughput

0.328

High

1326648

KIF2B
Kinesin-like protein KIF2B

2

0

High-throughput

0.328

High

1346718

JOS2
Josephin-2

2

0

High-throughput

0.328

High

1396461

F167A
Protein FAM167A

2

0

High-throughput

0.328

High

1458424

LAMP3
Lysosome-associated membrane glycoprotein 3

2

0

High-throughput

0.328

High

1359135

PIHD2
PIH1 domain-containing protein 2

2

0

High-throughput

0.316

High

789239

NUP62
Nuclear pore glycoprotein p62

2

0

High-throughput

0.313

High

1399553

MIA2
Melanoma inhibitory activity protein 2

2

0

High-throughput

0.288

High

136732

TRAF5
TNF receptor-associated factor 5

1

0

High-throughput

0.282

High

64393

CDHR4
Cadherin-related family member 4

1

0

High-throughput

0.279

Low

608374

EGLN
Endoglin

1

0

High-throughput

0.279

Low

1150382

TGIF1
Homeobox protein TGIF1

1

0

High-throughput

0.279

Low

1179874

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1243437

CNKR3
Connector enhancer of kinase suppressor of ras 3

1

0

High-throughput

0.279

Low

1252035

TRI72
Tripartite motif-containing protein 72

1

0

High-throughput

0.279

Low

1340041

O13G1
Olfactory receptor 13G1

1

0

High-throughput

0.279

Low

1371936

STMN2
Stathmin-2

1

0

High-throughput

0.279

Low

1387119

REPS1
RalBP1-associated Eps domain-containing protein 1

1

0

High-throughput

0.279

Low

1390897

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.279

Low

1458425

COF2
Cofilin-2

1

0

High-throughput

0.279

Low

675191

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.249

Low

774681

BASI
Basigin

1

0

High-throughput

0.249

Low

1399114

SCLT1
Sodium channel and clathrin linker 1

1

0

High-throughput

0.249

Low

1458423

A4GCT
Alpha-1,4-N-acetylglucosaminyltransferase

1

0

High-throughput

0.249

Low

437813

HEPS
Serine protease hepsin

1

0

High-throughput

0.232

Low

1167128

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low

1400937

VPS35
Vacuolar protein sorting-associated protein 35

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025