Protein: COMD5
COMM domain-containing protein 5 (Hypertension-related calcium-regulated gene protein) (HCaRG)

Gene: COMD5, COMMD5
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q9GZQ3

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1428335

COMDA
COMM domain-containing protein 10

6

4

Small-scale

0.942

High

257172

CCD22
Coiled-coil domain-containing protein 22

7

0

Small-scale

0.916

High

1328844

COMD1
COMM domain-containing protein 1

5

0

Small-scale

0.880

High

1428325

COMD4
COMM domain-containing protein 4

5

0

High-throughput

0.877

High

1428330

COMD3
COMM domain-containing protein 3

4

0

High-throughput

0.846

High

1428328

COMD8
COMM domain-containing protein 8

4

0

High-throughput

0.841

High

1278361

COMD6
COMM domain-containing protein 6

3

0

High-throughput

0.811

High

1428329

COMD9
COMM domain-containing protein 9

3

0

Small-scale

0.787

High

1201154

CCD93
Coiled-coil domain-containing protein 93

5

0

Small-scale

0.774

High

1293503

COMD2
COMM domain-containing protein 2

4

0

High-throughput

0.753

High

1428331

VPS29
Vacuolar protein sorting-associated protein 29

4

0

High-throughput

0.667

High

1291793

COMD7
COMM domain-containing protein 7

2

0

High-throughput

0.649

High

626357

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

2

Small-scale

0.536

High

1030033

RELB
Transcription factor RelB

1

2

Small-scale

0.536

High

1045744

TF65
Transcription factor p65

1

2

Small-scale

0.536

High

1257760

VP13C
Intermembrane lipid transfer protein VPS13C

1

1

High-throughput

0.536

High

171105

VP26C
Vacuolar protein sorting-associated protein 26C

1

0

High-throughput

0.513

High

187556

FANCA
Fanconi anemia group A protein

1

0

High-throughput

0.513

High

238609

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.513

High

282778

E2F6
Transcription factor E2F6

1

0

High-throughput

0.513

High

425955

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

0

High-throughput

0.513

High

944853

PCBP3
Poly(rC)-binding protein 3

1

0

High-throughput

0.513

High

1006692

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.513

High

1025841

BORG5
Cdc42 effector protein 1

1

0

High-throughput

0.513

High

1122864

TFDP1
Transcription factor Dp-1

1

0

High-throughput

0.513

High

1162119

DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

1

0

High-throughput

0.513

High

1215013

INT11
Integrator complex subunit 11

1

0

High-throughput

0.513

High

1259486

TBA1A
Tubulin alpha-1A chain

1

0

High-throughput

0.513

High

1277522

MON2
Protein MON2 homolog

1

0

High-throughput

0.513

High

1336168

SMG8
Nonsense-mediated mRNA decay factor SMG8

1

0

High-throughput

0.513

High

1371925

STMN2
Stathmin-2

1

0

High-throughput

0.513

High

1401759

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

0

High-throughput

0.513

High

1416752

BBS2
BBSome complex member BBS2

1

0

High-throughput

0.513

High

1428326

ESRP2
Epithelial splicing regulatory protein 2

1

0

High-throughput

0.513

High

1428327

RNF12
E3 ubiquitin-protein ligase RLIM

1

0

High-throughput

0.513

High

1428334

MTO1
5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial

1

0

High-throughput

0.513

High

1281228

VP13B
Intermembrane lipid transfer protein VPS13B

1

1

High-throughput

0.489

High

1428324

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

789216

NUP62
Nuclear pore glycoprotein p62

1

0

High-throughput

0.426

High

1349633

DEN10
DENN domain-containing protein 10

3

0

High-throughput

0.345

High

1277149

VP35L
VPS35 endosomal protein-sorting factor-like

2

0

High-throughput

0.313

High

945092

RAB25
Ras-related protein Rab-25

1

0

High-throughput

0.279

Low

1129300

BLTP2
Bridge-like lipid transfer protein family member 2

1

0

High-throughput

0.279

Low

1179851

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1191968

TBB8
Tubulin beta-8 chain

1

0

High-throughput

0.279

Low

1243431

CNKR3
Connector enhancer of kinase suppressor of ras 3

1

0

High-throughput

0.279

Low

1324957

VW5B2
von Willebrand factor A domain-containing protein 5B2

1

0

High-throughput

0.279

Low

1340036

O13G1
Olfactory receptor 13G1

1

0

High-throughput

0.279

Low

1364058

NICA
Nicastrin

1

0

High-throughput

0.279

Low

1386082

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

1

0

High-throughput

0.279

Low

1397802

ODAD1
Outer dynein arm-docking complex subunit 1

1

0

High-throughput

0.279

Low

1405023

NEUR1
Sialidase-1

1

0

High-throughput

0.279

Low

1428332

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.279

Low

1428333

MA1B1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025