HitPredict

Interactor 1: CHM4B (Q9H444)
Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (SNF7 homolog associated with Alix 1) (SNF7-2) (hSnf7-2) (Vacuolar protein sorting-associated protein 32-2) (Vps32-2) (hVps32-2)
Gene: CHMP4B

Interactor 2: CHMP5 (Q9NZZ3)
Charged multivesicular body protein 5 (Chromatin-modifying protein 5) (SNF7 domain-containing protein 2) (Vacuolar protein sorting-associated protein 60) (Vps60) (hVps60)
Gene: CHMP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.858

The method score is based on:

Property Details
Experiments 26496610, 40437099, 16730941
Identification Methods affinity chromatography technology, cross-linking study, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Snf7~Snf7
Common GO terms GO:0000421 - autophagosome membrane
GO:0000776 - kinetochore
GO:0000815 - ESCRT III complex
GO:0001778 - plasma membrane repair
GO:0005643 - nuclear pore
and 31 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 224
Hs

1 219
+ Hs
+ Ce
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ At
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025