Interactor 1: YTDC2 (Q9H6S0)
3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (YTH domain-containing protein 2) (hYTHDC2)
Gene: YTHDC2
Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DEAD~DEAD, DEAD~Helicase_C, HA2_C~Helicase_C, DEAD~HA2_N, HA2_N~Helicase_C, Helicase_C~Helicase_C, Helicase_C~OB_NTP_bind |
| Common GO terms | GO:0003723 - RNA binding GO:0005524 - ATP binding GO:0016887 - ATP hydrolysis activity |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025