HitPredict

Interactor 1: WN10B (O00744)
Protein Wnt-10b (Protein Wnt-12)
Gene: WNT10B

Interactor 2: WLS (Q5T9L3)
Protein wntless homolog (Integral membrane protein GPR177) (Protein evenness interrupted homolog) (EVI) (Putative NF-kappa-B-activating protein 373)
Gene: WLS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	WLS-like_TM~wnt, WLS_GOLD~wnt
Common GO terms	GO:0090263 - positive regulation of canonical Wnt signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 389 Hs			1 541
+	Mm
		605279 WNT3_MOUSE (24-389): 2.28e-153: 438: 36.34		WLS_MOUSE (1-541): 0: 812: 96.12
+	Hs
		942158 WNT3A_HUMAN (11-389): 4.64e-154: 439: 36.15		WLS_HUMAN (1-541): 0: 811: 100.00
+	Mm
		652165 WNT5A_MOUSE (15-389): 8.97e-148: 425: 33.42		WLS_MOUSE (1-541): 0: 812: 96.12
+	Hs
		833469 WNT5A_HUMAN (15-389): 6.68e-148: 425: 33.42		WLS_HUMAN (1-541): 0: 811: 100.00
+	Hs
		1214910 WNT5B_HUMAN (26-389): 6.87e-146: 419: 34.14		WLS_HUMAN (1-541): 0: 811: 100.00
+	Hs
		942182 WNT4_HUMAN (17-389): 1.5e-145: 418: 37.73		WLS_HUMAN (1-541): 0: 811: 100.00
+	Hs
		942202 WNT7B_HUMAN (30-389): 1.63e-145: 418: 37.06		WLS_HUMAN (1-541): 0: 811: 100.00
+	Hs
		483676 WNT2_HUMAN (43-389): 1.6e-144: 416: 38.11		WLS_HUMAN (1-541): 0: 811: 100.00
+	Hs
		144099 WNT7A_HUMAN (37-389): 3.66e-144: 414: 36.67		WLS_HUMAN (1-541): 0: 811: 100.00
+	Mm
		409208 WNT1_MOUSE (50-388): 1.64e-134: 391: 39.54		WLS_MOUSE (1-541): 0: 812: 96.12
+	Hs
		411162 WNT1_HUMAN (50-388): 1.84e-134: 391: 39.54		WLS_HUMAN (1-541): 0: 811: 100.00
+	Hs
		1214923 WNT16_HUMAN (19-389): 4.16e-130: 379: 32.12		WLS_HUMAN (1-541): 0: 811: 100.00
+	Hs
		167452 WNT9A_HUMAN (1-389): 4.15e-117: 346: 30.10		WLS_HUMAN (1-541): 0: 811: 100.00
+	Hs
		1214909 WNT8A_HUMAN (63-388): 3.41e-115: 341: 31.09		WLS_HUMAN (1-541): 0: 811: 100.00
+	Hs
		167480 WNT9B_HUMAN (43-389): 1.85e-114: 339: 33.33		WLS_HUMAN (1-541): 0: 811: 100.00
+	Hs
		1214889 WNT8B_HUMAN (70-388): 1.83e-106: 318: 32.02		WLS_HUMAN (1-541): 0: 811: 100.00
+	Dm
		703410 WNT2_DROME (30-389): 3.51e-120: 354: 33.16		WLS_DROME (1-535): 0: 642: 40.82
+	Dm
		1378052 Q9VM26_DROME (16-388): 2.08e-118: 352: 29.38		WLS_DROME (1-535): 0: 642: 40.82
+	Dm
		827126 WNT4_DROME (48-389): 4.29e-101: 311: 28.25		WLS_DROME (1-535): 0: 642: 40.82
+	Dm
		703422 WNT5_DROME (48-226): 5.25e-45: 167: 27.37		WLS_DROME (1-535): 0: 642: 40.82