Interactor 1: AGRL3 (Q9HAR2)
Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3)
Gene: ADGRL3
Interactor 2: FLRT3 (Q9NZU0)
Leucine-rich repeat transmembrane protein FLRT3 (Fibronectin-like domain-containing leucine-rich transmembrane protein 3)
Gene: FLRT3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.51 | 1.00 | 0.716 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26235030 |
| Identification Methods | x-ray crystallography, bio-layer interferometry, molecular sieving |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_8~OLF, Gal_Lectin~LRR_8 |
| Common GO terms | GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0007416 - synapse assembly GO:0098742 - cell-cell adhesion via plasma-membrane adhesion molecules GO:0098978 - glutamatergic synapse |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025