HitPredict

Interactor 1: LAR4 (Q9I7T7)
La-related protein Larp4B (La ribonucleoprotein domain family member Larp4B)
Gene: Larp4B

Interactor 2: CPSF6 (Q9VSH4)
Cleavage and polyadenylation specificity factor subunit 6
Gene: CPSF6

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.80	0.659

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1531 Dm			1 652
+	Dm
		674038 LAR4_DROME (1-1531): 0: 1751: 100.00		BRM_DROME (275-642): 1.44e-45: 176: 14.62
+	Hs
		550338 LARP4_HUMAN (233-605): 1.53e-98: 335: 38.32		PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15
+	Hs
		1102038 LAR4B_HUMAN (233-603): 3.56e-90: 312: 35.20		PABP4_HUMAN (79-363): 1.21e-44: 171: 11.79
+	Hs
		550388 LAR4B_HUMAN (233-603): 3.56e-90: 312: 35.20		PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15
+	Hs
		274174 LARP4_HUMAN (233-605): 1.53e-98: 335: 38.32		ANR17_HUMAN (166-481): 7.94e-25: 112: 17.93
+	Hs
		274212 LAR4B_HUMAN (233-603): 3.56e-90: 312: 35.20		ANR17_HUMAN (166-481): 7.94e-25: 112: 17.93
+	Hs
		431115 LA_HUMAN (256-456): 3.15e-49: 183: 18.39		PABP4_HUMAN (79-363): 1.21e-44: 171: 11.79
+	Hs
		1101996 LARP1_HUMAN (245-792): 2.86e-40: 165: 16.20		PABP4_HUMAN (79-363): 1.21e-44: 171: 11.79
+	Hs
		1101980 LARP7_HUMAN (268-415): 3.03e-41: 163: 25.61		PABP4_HUMAN (79-363): 1.21e-44: 171: 11.79
+	Hs
		550331 LARP1_HUMAN (245-792): 2.86e-40: 165: 16.20		PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15
+	Hs
		550310 LARP7_HUMAN (268-415): 3.03e-41: 163: 25.61		PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15
+	Hs
		1194374 LARP7_HUMAN (268-415): 3.03e-41: 163: 25.61		PABP3_HUMAN (79-364): 1.48e-36: 147: 12.59
+	Hs
		1194430 LARP7_HUMAN (268-415): 3.03e-41: 163: 25.61		CHD7_HUMAN (39-513): 9.51e-36: 147: 13.42
+	Hs
		1194132 LARP7_HUMAN (268-415): 3.03e-41: 163: 25.61		PAP1L_HUMAN (78-335): 7.51e-36: 145: 13.03
+	Hs
		1160148 LARP7_HUMAN (268-415): 3.03e-41: 163: 25.61		CPSF6_HUMAN (1-556): 2.03e-35: 142: 35.89
+	Hs
		431237 LA_HUMAN (256-456): 3.15e-49: 183: 18.39		DIDO1_HUMAN (145-650): 1.49e-27: 121: 16.67
+	Hs
		550323 LAR1B_HUMAN (234-410): 8.25e-34: 143: 23.73		PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15