Interactor 1: DPOE4 (Q9NR33)
DNA polymerase epsilon subunit 4 (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12)
Gene: POLE4
Interactor 2: DPOE3 (Q9NRF9)
DNA polymerase epsilon subunit 3 (Arsenic-transactivated protein) (AsTP) (Chromatin accessibility complex 17 kDa protein) (CHRAC-17) (HuCHRAC17) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17)
Gene: POLE3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.81 | 1.00 | 0.902 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 33961781, 10801849, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CBFD_NFYB_HMF~CBFD_NFYB_HMF |
| Common GO terms | GO:0003887 - DNA-directed DNA polymerase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006261 - DNA-templated DNA replication GO:0008622 - epsilon DNA polymerase complex and 2 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
