HitPredict

Interactor 1: TOPRS (Q9NS56)
E3 ubiquitin-protein ligase Topors (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Topors) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3)
Gene: TOPORS

Interactor 2: ZRAN1 (Q9UGI0)
Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1)
Gene: ZRANB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35944360
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1045 Hs			1 708
+	Hs
		1358518 DC2I1_HUMAN (591-1037): 4.69e-27: 121: 12.32		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1247991 ANR11_HUMAN (465-1032): 1.48e-25: 117: 10.73		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1228925 S31H1_HUMAN (424-786): 3.57e-23: 109: 13.22		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1341043 THOC2_HUMAN (286-795): 5.75e-19: 95.2: 10.99		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1365863 PRP16_HUMAN (543-955): 3.16e-18: 92.8: 10.32		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1351609 MIPT3_HUMAN (524-957): 5.19e-18: 91.3: 13.32		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1235688 NIPBL_HUMAN (312-903): 1.01e-15: 84.8: 9.88		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1405507 SCAFB_HUMAN (454-795): 1.71e-15: 84: 11.85		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1121907 EIF3A_HUMAN (540-929): 4.18e-14: 79.4: 7.79		ZRAN1_HUMAN (1-697): 0: 987: 100.00