Protein: VWDE
von Willebrand factor D and EGF domain-containing protein

Gene: VWDE
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q8N2E2

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0009986 - cell surface

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

567915

PRG2
Bone marrow proteoglycan

3

11

High-throughput

0.667

High

1278864

LYZL2
Lysozyme-like protein 2

2

2

High-throughput

0.628

High

1324210

LYPD1
Ly6/PLAUR domain-containing protein 1

2

3

High-throughput

0.628

High

1324229

PSG8
Pregnancy-specific beta-1-glycoprotein 8

2

10

High-throughput

0.628

High

1205422

DB121
Beta-defensin 121

2

0

High-throughput

0.602

High

65947

LIRA5
Leukocyte immunoglobulin-like receptor subfamily A member 5

1

5

High-throughput

0.536

High

164771

GDF8
Growth/differentiation factor 8

1

6

High-throughput

0.536

High

231054

VEGFD
Vascular endothelial growth factor D

1

4

High-throughput

0.536

High

240198

KLK8
Kallikrein-8

1

16

High-throughput

0.536

High

388727

C1QB
Complement C1q subcomponent subunit B

1

8

High-throughput

0.536

High

416630

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

1

High-throughput

0.536

High

455655

KLK3
Prostate-specific antigen

1

12

High-throughput

0.536

High

469813

CATG
Cathepsin G

1

14

High-throughput

0.536

High

506873

CFC1
Cryptic protein

1

3

High-throughput

0.536

High

570695

EDN3
Endothelin-3

1

4

High-throughput

0.536

High

651604

IBP4
Insulin-like growth factor-binding protein 4

1

8

High-throughput

0.536

High

663560

CMA1
Chymase

1

15

High-throughput

0.536

High

702405

CYTD
Cystatin-D

1

5

High-throughput

0.536

High

731878

CEAM8
Cell adhesion molecule CEACAM8

1

8

High-throughput

0.536

High

757358

RNAS4
Ribonuclease 4

1

1

High-throughput

0.536

High

889931

VEGFB
Vascular endothelial growth factor B

1

4

High-throughput

0.536

High

1022261

FBLN2
Fibulin-2

1

19

High-throughput

0.536

High

1099631

NOGG
Noggin

1

1

High-throughput

0.536

High

1103099

MFAP5
Microfibrillar-associated protein 5

1

3

High-throughput

0.536

High

1248559

LYPD4
Ly6/PLAUR domain-containing protein 4

1

1

High-throughput

0.536

High

1248768

LYZL1
Lysozyme-like protein 1

1

2

High-throughput

0.536

High

1249671

IGFL3
Insulin growth factor-like family member 3

1

5

High-throughput

0.536

High

1308263

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

1

High-throughput

0.536

High

1324215

NET5
Netrin-5

1

20

High-throughput

0.536

High

1324216

OIT3
Oncoprotein-induced transcript 3 protein

1

20

High-throughput

0.536

High

1324217

ESPB1
Epididymal sperm-binding protein 1

1

5

High-throughput

0.536

High

1324218

LCFC1
Sperm-egg fusion protein LLCFC1

1

2

High-throughput

0.536

High

1324220

CCL19
C-C motif chemokine 19

1

4

High-throughput

0.536

High

1324222

SIRPD
Signal-regulatory protein delta

1

3

High-throughput

0.536

High

1324223

CST11
Cystatin-11

1

5

High-throughput

0.536

High

1324225

GREM2
Gremlin-2

1

1

High-throughput

0.536

High

1324231

HYOU1
Hypoxia up-regulated protein 1

1

1

High-throughput

0.536

High

631814

MCH
Pro-MCH [Cleaved into: Neuropeptide-glycine-glutamic acid

1

0

High-throughput

0.513

High

634972

NTF3
Neurotrophin-3

1

0

High-throughput

0.513

High

843130

CXCL5
C-X-C motif chemokine 5

1

0

High-throughput

0.513

High

1025932

NDP
Norrin

1

0

High-throughput

0.513

High

1181046

DB135
Beta-defensin 135

1

0

High-throughput

0.513

High

1324214

LPD6B
Ly6/PLAUR domain-containing protein 6B

1

0

High-throughput

0.513

High

1324219

IL17F
Interleukin-17F

1

0

High-throughput

0.513

High

1324226

PROK2
Prokineticin-2

1

0

High-throughput

0.513

High

64371

CDHR4
Cadherin-related family member 4

1

4

High-throughput

0.489

High

248407

GDF9
Growth/differentiation factor 9

1

8

High-throughput

0.489

High

634784

GRAH
Granzyme H

1

14

High-throughput

0.489

High

647378

IDS
Iduronate 2-sulfatase

1

5

High-throughput

0.489

High

841568

I12R1
Interleukin-12 receptor subunit beta-1

1

6

High-throughput

0.489

High

945898

INHBE
Inhibin beta E chain

1

6

High-throughput

0.489

High

1147374

EPHA7
Ephrin type-A receptor 7

1

9

High-throughput

0.489

High

1278995

TAFA5
Chemokine-like protein TAFA-5

1

3

High-throughput

0.489

High

1324211

TAFA2
Chemokine-like protein TAFA-2

1

3

High-throughput

0.489

High

1324212

TM87A
Transmembrane protein 87A

1

1

High-throughput

0.489

High

1324221

BOC
Brother of CDO

1

7

High-throughput

0.489

High

1324224

KLK15
Kallikrein-15

1

12

High-throughput

0.489

High

1324227

SDF2L
Stromal cell-derived factor 2-like protein 1

1

2

High-throughput

0.489

High

1324230

CCL26
C-C motif chemokine 26

1

4

High-throughput

0.489

High

1113672

CUL3
Cullin-3

1

9

High-throughput

0.437

High

1324213

FXL13
F-box and leucine-rich repeat protein 13

1

1

Small-scale

0.437

High

1324228

FBX6
F-box only protein 6

1

14

High-throughput

0.437

High

1160414

TAZ
Tafazzin

3

0

High-throughput

0.347

High

351708

SG1D1
Secretoglobin family 1D member 1

2

0

High-throughput

0.328

High

399457

TRGV3
T cell receptor gamma variable 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025