Protein: JAG1
Protein jagged-1 (Jagged1) (hJ1) (CD antigen CD339)

Gene: JAG1
Organism: Homo sapiens
Interactions: 42
UniProt ID: P78504

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001709 - cell fate determination
GO:0001953 - negative regulation of cell-matrix adhesion
GO:0001974 - blood vessel remodeling
GO:0002011 - morphogenesis of an epithelial sheet

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

857407

NOTC1
Neurogenic locus notch homolog protein 1

4

19

Small-scale

0.899

High

1008015

NOTC2
Neurogenic locus notch homolog protein 2

3

16

Small-scale

0.876

High

1008030

NOTC3
Neurogenic locus notch homolog protein 3

2

17

Small-scale

0.768

High

584677

MCP
Membrane cofactor protein

1

7

Small-scale

0.716

High

1008018

MIB1
E3 ubiquitin-protein ligase MIB1

2

20

Small-scale

0.646

High

302222

NEUL1
E3 ubiquitin-protein ligase NEURL1

2

19

Small-scale

0.624

High

410766

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

18

High-throughput

0.618

High

480766

LEG1
Galectin-1

2

10

High-throughput

0.601

High

1008012

ADA17
Disintegrin and metalloproteinase domain-containing protein 17

1

16

Small-scale

0.501

High

1008029

FBX2
F-box only protein 2

1

14

High-throughput

0.489

High

464436

TSP1
Thrombospondin-1

1

18

Small-scale

0.481

High

936294

AFAD
Afadin

1

20

Small-scale

0.481

High

127049

APBB1
Amyloid beta precursor protein binding family B member 1

1

1

Small-scale

0.479

High

374520

RASH
GTPase HRas

1

10

High-throughput

0.479

High

375397

RASK
GTPase KRas

1

15

High-throughput

0.479

High

466201

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

580983

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

774285

BASI
Basigin

1

5

High-throughput

0.479

High

953388

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

977928

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

988269

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

1008013

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

1008014

CAV1
Caveolin-1

1

3

High-throughput

0.479

High

1008016

CUL3
Cullin-3

1

13

High-throughput

0.479

High

1008019

HTRA1
Serine protease HTRA1

1

3

Small-scale

0.479

High

1008021

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

9

Small-scale

0.479

High

1008022

SEC62
Translocation protein SEC62

1

3

High-throughput

0.479

High

1008023

ACE2
Angiotensin-converting enzyme 2

1

2

Small-scale

0.479

High

1008025

P63
Tumor protein 63

1

4

Small-scale

0.479

High

1008026

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1008027

ELOV5
Very long chain fatty acid elongase 5

1

4

High-throughput

0.479

High

1008031

ALK
ALK tyrosine kinase receptor

1

9

High-throughput

0.479

High

887410

CEBPD
CCAAT/enhancer-binding protein delta

1

0

Small-scale

0.458

High

1008024

SDCB2
Syntenin-2

1

7

Small-scale

0.457

High

697839

CALR
Calreticulin

1

4

Small-scale

0.445

High

698578

CALX
Calnexin

1

4

Small-scale

0.445

High

872192

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.445

High

948781

CD81
CD81 antigen

1

7

High-throughput

0.445

High

169509

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

4

Small-scale

0.437

High

1008017

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1008020

FBXW7
F-box/WD repeat-containing protein 7

1

6

Small-scale

0.437

High

1008028

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.437

High


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Last updated: 11Aug2025