HitPredict

Interactor 1: NCBP2 (Q9V3L6)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20)
Gene: Cbp20

Interactor 2: CPSF6 (Q9VSH4)
Cleavage and polyadenylation specificity factor subunit 6
Gene: CPSF6

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003729 - mRNA binding GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 154 Dm			1 652
+	Dm
		1472290 Q9VE52_DROME (18-138): 8.84e-35: 126: 28.10		CPSF6_DROME (1-652): 4.98e-59: 211: 100.00
+	Hs
		911574 NCBP2_HUMAN (5-146): 1.96e-40: 134: 76.06		PABP4_HUMAN (79-363): 1.21e-44: 171: 11.79
+	Dm
		1464258 Q9V3T8_DROME (31-106): 1.45e-21: 87.8: 38.16		CPSF6_DROME (1-652): 4.98e-59: 211: 100.00
+	Hs
		550190 NCBP2_HUMAN (5-146): 1.96e-40: 134: 76.06		PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15
+	Hs
		911605 NCBP2_HUMAN (5-146): 1.96e-40: 134: 76.06		CPSF6_HUMAN (1-556): 2.03e-35: 142: 35.89
+	Hs
		1160289 CSTFT_HUMAN (20-148): 9.77e-36: 131: 25.39		CPSF6_HUMAN (1-556): 2.03e-35: 142: 35.89
+	Hs
		750424 CSTF2_HUMAN (17-148): 4.53e-35: 129: 26.32		CPSF6_HUMAN (1-556): 2.03e-35: 142: 35.89
+	Hs
		1090216 ELAV2_HUMAN (3-140): 2.1e-24: 98.4: 19.21		PABP4_HUMAN (79-363): 1.21e-44: 171: 11.79
+	Hs
		550262 PABP4_HUMAN (2-154): 5.37e-26: 104: 18.59		PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15
+	Hs
		1102095 PABP4_HUMAN (2-154): 5.37e-26: 104: 18.59		PABP3_HUMAN (79-364): 1.48e-36: 147: 12.59
+	Hs
		550311 PAP1L_HUMAN (2-113): 2.11e-25: 102: 20.54		PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15
+	Hs
		1197178 PAP1L_HUMAN (2-113): 2.11e-25: 102: 20.54		PABP3_HUMAN (79-364): 1.48e-36: 147: 12.59
+	Hs
		550097 PABP1_HUMAN (2-154): 8.75e-25: 100: 18.59		PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15
+	Hs
		550250 ELAV2_HUMAN (3-140): 2.1e-24: 98.4: 19.21		PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15
+	Hs
		550464 PABP1_HUMAN (2-154): 8.75e-25: 100: 18.59		PABP3_HUMAN (79-364): 1.48e-36: 147: 12.59
+	Hs
		274123 NCBP2_HUMAN (5-146): 1.96e-40: 134: 76.06		ANR17_HUMAN (166-481): 7.94e-25: 112: 17.93
+	Hs
		686645 ELAV4_HUMAN (28-113): 1.31e-24: 99.1: 27.91		DIDO1_HUMAN (145-650): 1.49e-27: 121: 16.67
+	Hs
		130408 NCBP2_HUMAN (5-146): 1.96e-40: 134: 76.06		SPT5H_HUMAN (42-262): 2.87e-09: 62.4: 14.22