Interactor 1: SYFB (Q9VCA5)
Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS)
Gene: beta-PheRS

Interactor 2: SYFA (Q9W3J5)
Phenylalanine--tRNA ligase alpha subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase alpha subunit) (PheRS)
Gene: alpha-PheRS

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains B3_4~tRNA-synt_2d, B5~tRNA-synt_2d, PhetRS_B1~tRNA-synt_2d, PheRS_DBD1~tRNA_synthFbeta, tRNA-synt_2d~tRNA_synthFbeta
Common GO terms GO:0000287 - magnesium ion binding
GO:0004826 - phenylalanine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006432 - phenylalanyl-tRNA aminoacylation
and 1 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 589
Dm

1 498
+ Hs
+ Ce
+ Sc
+ Mt
+ Ec
+ Nv
+ Tt
+ Mp

Service provided by Combinatics, Japan

Last updated: 11Aug2025