HitPredict

Interactor 1: MCM5 (Q9VGW6)
DNA replication licensing factor Mcm5 (EC 3.6.4.12) (Minichromosome maintenance 5 protein) (DmMCM5)
Gene: MCM5

Interactor 2: MCMBP (Q9VM60)
Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein)
Gene: CG3430

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	14605208, 22036573, 38944040
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 733 Dm			1 605
+	Hs
		756037 MCM5_HUMAN (1-732): 0: 803: 68.25		MCMBP_HUMAN (1-594): 0: 774: 35.27
+	Hs
		888292 MCM2_HUMAN (29-731): 0: 696: 30.03		MCMBP_HUMAN (1-594): 0: 774: 35.27
+	Hs
		755778 MCM4_HUMAN (5-730): 0: 677: 30.73		MCMBP_HUMAN (1-594): 0: 774: 35.27
+	Hs
		756326 MCM7_HUMAN (26-729): 0: 657: 29.44		MCMBP_HUMAN (1-594): 0: 774: 35.27
+	Hs
		1128270 MCM6_HUMAN (6-728): 0: 649: 28.89		MCMBP_HUMAN (1-594): 0: 774: 35.27
+	Mm
		670060 MCM3_MOUSE (15-729): 0: 635: 28.46		MCMBP_MOUSE (1-594): 0: 765: 34.80
+	At
		306504 MCM5_ARATH (1-731): 0: 696: 48.31		MCMBP_ARATH (19-594): 0: 626: 30.17
+	At
		1082447 MCM4_ARATH (18-726): 0: 657: 30.70		MCMBP_ARATH (19-594): 0: 626: 30.17
+	At
		1197431 MCM3_ARATH (31-657): 0: 656: 29.80		MCMBP_ARATH (19-594): 0: 626: 30.17
+	At
		1197434 MCM2_ARATH (23-703): 0: 655: 30.53		MCMBP_ARATH (19-594): 0: 626: 30.17
+	At
		847376 MCM7_ARATH (23-724): 0: 652: 31.52		MCMBP_ARATH (19-594): 0: 626: 30.17
+	At
		103710 MCM6_ARATH (13-690): 0: 641: 29.71		MCMBP_ARATH (19-594): 0: 626: 30.17
+	Sp
		314182 MCM5_SCHPO (2-731): 0: 680: 45.85		YFF4_SCHPO (9-589): 1.31e-173: 503: 20.17
+	Sp
		314181 MCM2_SCHPO (24-666): 0: 657: 32.88		YFF4_SCHPO (9-589): 1.31e-173: 503: 20.17
+	Sp
		314179 MCM4_SCHPO (19-731): 0: 651: 29.06		YFF4_SCHPO (9-589): 1.31e-173: 503: 20.17
+	Sp
		268828 MCM7_SCHPO (15-730): 0: 627: 28.31		YFF4_SCHPO (9-589): 1.31e-173: 503: 20.17