HitPredict

Interactor 1: MCM4 (P33991)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21)
Gene: MCM4

Interactor 2: MCMBP (Q9BTE3)
Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein)
Gene: MCMBP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.717

Property	Details
Experiments	22540012, 17296731, 25036637, 24299456
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 863 Hs			1 642
+	Hs
		888292 MCM2_HUMAN (2-839): 0: 762: 27.95		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	Hs
		756037 MCM5_HUMAN (133-846): 0: 698: 30.23		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	Hs
		1128270 MCM6_HUMAN (138-842): 0: 675: 26.97		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	Hs
		1413476 MCM8_HUMAN (94-863): 0: 663: 24.76		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	Hs
		756326 MCM7_HUMAN (158-841): 0: 660: 29.88		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	At
		1082447 MCM4_ARATH (40-863): 0: 762: 42.52		MCMBP_ARATH (4-632): 0: 685: 31.38
+	At
		1197434 MCM2_ARATH (28-862): 0: 731: 26.72		MCMBP_ARATH (4-632): 0: 685: 31.38
+	Dm
		1475318 MCM5_DROME (132-846): 0: 683: 31.41		MCMBP_DROME (1-632): 0: 724: 35.47
+	At
		103710 MCM6_ARATH (153-862): 0: 662: 28.44		MCMBP_ARATH (4-632): 0: 685: 31.38
+	At
		847376 MCM7_ARATH (155-841): 0: 648: 30.84		MCMBP_ARATH (4-632): 0: 685: 31.38
+	At
		1197431 MCM3_ARATH (175-861): 0: 644: 29.13		MCMBP_ARATH (4-632): 0: 685: 31.38
+	Sp
		314179 MCM4_SCHPO (6-855): 0: 749: 42.14		YFF4_SCHPO (341-623): 6.71e-102: 321: 25.09
+	Sp
		314181 MCM2_SCHPO (28-772): 0: 710: 27.96		YFF4_SCHPO (341-623): 6.71e-102: 321: 25.09
+	At
		306504 MCM5_ARATH (208-799): 4.34e-97: 321: 35.52		MCMBP_ARATH (4-632): 0: 685: 31.38
+	Sp
		314182 MCM5_SCHPO (156-861): 0: 681: 31.65		YFF4_SCHPO (341-623): 6.71e-102: 321: 25.09
+	Sp
		314183 MCM6_SCHPO (95-863): 0: 653: 28.89		YFF4_SCHPO (341-623): 6.71e-102: 321: 25.09
+	Sp
		268828 MCM7_SCHPO (250-764): 1.32e-96: 320: 37.95		YFF4_SCHPO (341-623): 6.71e-102: 321: 25.09