Protein: MCMBP
Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein)

Gene: MCMBP
Organism: Homo sapiens
Interactions: 109
UniProt ID: Q9BTE3

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006261 - DNA-templated DNA replication

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

756326

MCM7
DNA replication licensing factor MCM7

9

17

Small-scale

0.762

High

669990

MCM3
DNA replication licensing factor MCM3

9

19

Small-scale

0.758

High

1128270

MCM6
DNA replication licensing factor MCM6

6

19

Small-scale

0.746

High

756037

MCM5
DNA replication licensing factor MCM5

6

16

Small-scale

0.745

High

888292

MCM2
DNA replication licensing factor MCM2

5

19

Small-scale

0.722

High

1121508

KEAP1
Kelch-like ECH-associated protein 1

5

1

Small-scale

0.717

High

755778

MCM4
DNA replication licensing factor MCM4

4

17

Small-scale

0.717

High

1106056

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

5

0

High-throughput

0.689

High

1413469

PRDC1
Phosphoribosyltransferase domain-containing protein 1

4

0

High-throughput

0.675

High

1413476

MCM8
DNA helicase MCM8

3

20

Small-scale

0.656

High

1371647

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

1

Small-scale

0.649

High

409200

ARLY
Argininosuccinate lyase

3

0

High-throughput

0.639

High

775468

DDIT3
DNA damage-inducible transcript 3 protein

3

0

High-throughput

0.639

High

921565

PGTB2
Geranylgeranyl transferase type-2 subunit beta

3

0

High-throughput

0.638

High

1272255

MCM10
Protein MCM10 homolog

3

0

High-throughput

0.638

High

1030809

DEF5
Defensin alpha 5

3

1

High-throughput

0.604

High

216531

SUV91
Histone-lysine N-methyltransferase SUV39H1

2

0

High-throughput

0.602

High

1025590

CDK16
Cyclin-dependent kinase 16

2

0

High-throughput

0.602

High

1213468

DCA12
DDB1- and CUL4-associated factor 12

2

0

High-throughput

0.602

High

1271526

DHX30
ATP-dependent RNA helicase DHX30

2

0

High-throughput

0.602

High

1350266

RHPN1
Rhophilin-1

2

0

High-throughput

0.602

High

1413465

WDR55
WD repeat-containing protein 55

2

0

High-throughput

0.602

High

1413477

SMC3
Structural maintenance of chromosomes protein 3

2

0

Small-scale

0.592

High

1114160

CUL3
Cullin-3

2

0

High-throughput

0.585

High

1143857

TCAL1
Transcription elongation factor A protein-like 1

2

0

High-throughput

0.585

High

589559

RFA2
Replication protein A 32 kDa subunit

2

1

Small-scale

0.584

High

1111236

SNW1
SNW domain-containing protein 1

2

0

High-throughput

0.580

High

948017

DEF1
Neutrophil defensin 1

2

1

High-throughput

0.574

High

132508

CDC7
Cell division cycle 7-related protein kinase

2

0

Small-scale

0.559

High

242763

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

696366

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

0

Small-scale

0.559

High

1411866

SLD5
DNA replication complex GINS protein SLD5

2

0

Small-scale

0.559

High

1413474

ZRAN1
Ubiquitin thioesterase ZRANB1

2

0

High-throughput

0.559

High

1413478

PSF2
DNA replication complex GINS protein PSF2

2

0

Small-scale

0.559

High

1209591

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

0

High-throughput

0.547

High

247420

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

1

High-throughput

0.536

High

274729

DNJB6
DnaJ homolog subfamily B member 6

1

1

High-throughput

0.536

High

1413471

MCM9
DNA helicase MCM9

1

20

High-throughput

0.536

High

862417

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.513

High

1036682

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

0

High-throughput

0.513

High

1100996

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

1161879

DUS5
Dual specificity protein phosphatase 5

1

0

High-throughput

0.513

High

1280173

TCPR1
Tectonin beta-propeller repeat-containing protein 1

1

0

High-throughput

0.513

High

1313593

DDX60
Probable ATP-dependent RNA helicase DDX60

1

0

High-throughput

0.513

High

1361574

ING5
Inhibitor of growth protein 5

1

0

High-throughput

0.513

High

1405588

TEAD3
Transcriptional enhancer factor TEF-5

1

0

High-throughput

0.513

High

1406977

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.513

High

1413463

TARA
TRIO and F-actin-binding protein

1

0

High-throughput

0.513

High

1413472

ORC3
Origin recognition complex subunit 3

1

0

Small-scale

0.513

High

831336

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

966821

1433G
14-3-3 protein gamma

1

2

High-throughput

0.479

High

1049725

1433F
14-3-3 protein eta

1

2

High-throughput

0.479

High

1096804

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

1405836

DNJC7
DnaJ homolog subfamily C member 7

1

1

High-throughput

0.479

High

1413460

TRAIP
E3 ubiquitin-protein ligase TRAIP

1

1

Small-scale

0.479

High

1413473

DBF4A
Protein DBF4 homolog A

1

0

Small-scale

0.460

High

176086

KDM6B
Lysine-specific demethylase 6B

1

0

Small-scale

0.458

High

260387

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

298954

DNJB5
DnaJ homolog subfamily B member 5

1

0

High-throughput

0.458

High

315957

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

325081

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

332769

EPM2A
Laforin

1

0

High-throughput

0.458

High

346264

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

373013

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

414525

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

537811

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

567475

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

719176

MPIP1
M-phase inducer phosphatase 1

1

0

High-throughput

0.458

High

769037

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

897957

CDK9
Cyclin-dependent kinase 9

1

0

High-throughput

0.458

High

927119

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

935071

TERA
Transitional endoplasmic reticulum ATPase

1

0

Small-scale

0.458

High

971003

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1067663

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1091837

TP4A2
Protein tyrosine phosphatase type IVA 2

1

0

High-throughput

0.458

High

1138577

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1151381

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.458

High

1178347

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1218570

MYSM1
Deubiquitinase MYSM1

1

0

Small-scale

0.458

High

1220761

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

1276722

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1311962

SKA3
Spindle and kinetochore-associated protein 3

1

0

Small-scale

0.458

High

1334850

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1380643

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1397379

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1413467

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1413470

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

330295

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.426

High

1315709

DND1
Dead end protein homolog 1

1

0

High-throughput

0.426

High

1413461

C1QT2
Complement C1q tumor necrosis factor-related protein 2

3

0

High-throughput

0.347

High

1279023

TAFA3
Chemokine-like protein TAFA-3

2

0

High-throughput

0.328

High

1247558

ZN474
Zinc finger protein 474

2

0

High-throughput

0.316

High

1413475

RWD2A
RWD domain-containing protein 2A

2

0

High-throughput

0.316

High

1208236

SPXN4
Sperm protein associated with the nucleus on the X chromosome N4

1

0

High-throughput

0.279

Low

1251680

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

1254138

CAN12
Calpain-12

1

0

High-throughput

0.279

Low

1315506

DAAF8
Dynein axonemal assembly factor 8

1

0

High-throughput

0.279

Low

1338049

WFD11
Protein WFDC11

1

0

High-throughput

0.279

Low

1413480

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.279

Low

168896

PLD2
Phospholipase D2

1

0

High-throughput

0.249

Low

412530

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1120099

COX17
Cytochrome c oxidase copper chaperone

1

0

High-throughput

0.249

Low

1255307

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1413462

RHBT2
Rho-related BTB domain-containing protein 2

1

0

High-throughput

0.249

Low

1413464

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1413466

MAGIX
PDZ domain-containing protein MAGIX

1

0

High-throughput

0.249

Low

1413468

TLR9
Toll-like receptor 9

1

0

Small-scale

0.249

Low

906343

GPC3
Glypican-3

1

0

High-throughput

0.232

Low

1413479

PCDG9
Protocadherin gamma-A9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025